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SJFδ

Catalog No.GC33238

SJF&delta ; est un lieur PROTAC à 10 atomes basé sur le ligand de von Hippel-Lindau. SJF&delta ; dégrade p38δ avec un DC50 de 46,17 nM, mais ne dégrade pas p38α, p38β ou p38γ.

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SJFδ Chemical Structure

Cas No.: 2254609-23-7

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38α with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].

[1]. Smith BE, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019 Jan 10;10(1):131.

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Average Rating: 5 ★★★★★ (Based on Reviews and 33 reference(s) in Google Scholar.)

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