GLPBio

Eslicarbazepine

Catalog No.: GC36008Purity:>99.00%
COASDSData Sheet
Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.

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Eslicarbazepine
Cas No.: 104746-04-5
10mM (in 1mL DMSO)In Stock
$39.00
1
5mgIn Stock
$35.00
1
10mgIn Stock
$56.00
1
25mgIn Stock
$105.00
1
50mgIn Stock
$161.00
1
100mgIn Stock
$245.00
1
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Description

Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.

Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel[1][2].

References:
[1]. Finelli E, et al. Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction. Eur Ann Allergy Clin Immunol. 2018 Sep;50(5):229-231.
[2]. Sibhghatulla Shaikh, et al. Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimer's Disease-Epilepsy Linkage via an Enzoinformatics Study. CNS & Neurological Disorders Drug Targets Volume 13 , Issue 7 , 2014.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
104746-04-5
SMILES
O=C(N)N1C2=CC=CC=C2C[C@@H](C3=CC=CC=C31)O
Molecular Formula
C15H14N2O2
Molecular Weight
254.28
Solubility
DMSO: 250 mg/mL (983.17 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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