Nanatinostat (Synonyms: CHR-3996) |
| カタログ番号GC36691 |
ナナチノスタット (CHR-3996) は、強力なクラス I 選択的経口活性ヒストン脱アセチル化酵素 (HDAC) 阻害剤であり、IC50 は 8 nM です。
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Cas No.: 1256448-47-1
Sample solution is provided at 25 µL, 10mM.
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Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM[1]. IC50:8 nM ( HDAC)[1]
[1]. Moffat D, et al. Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor. J Med Chem. 2010 Dec 23;53(24):8663-78.
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