>>Signaling Pathways>> DNA Damage/DNA Repair>> HDAC>>Nanatinostat

Nanatinostat (Synonyms: CHR-3996)

Catalog No.GC36691

나나티노스타트(CHR-3996)는 IC50이 8nM인 강력한 클래스 I 선택적 경구 활성 히스톤 데아세틸라제(HDAC) 억제제입니다.

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Nanatinostat Chemical Structure

Cas No.: 1256448-47-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM[1]. IC50:8 nM ( HDAC)[1]

[1]. Moffat D, et al. Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor. J Med Chem. 2010 Dec 23;53(24):8663-78.

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