GLPBio

Ferroptosis

Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.

Products Related to Ferroptosis(211)

  • GC38203 structure
    GC38203WJ460
    CAS: 1415251-36-3
    Purity: >98.00%

    WJ460은 MYOF와 직접 상호 작용하는 강력한 myoferlin(MYOF) 억제제이다.

  • GC38429 structure
    GC38429Dihydroartemisinic acid
    CAS: 85031-59-0
    Purity: >99.00%

    Dihydroartemisinic acid(Dihydroqinghao acid)는 항말라리아제 Artemisinin의 생합성 전구체입니다.

  • GC40193 structure
    GC40193UAMC-3203
    CAS: 2271358-64-4
    Purity: >98.00%

    UAMC-3203은 IC50이 12nM인 강력하고 선택적인 Ferroptosis 억제제입니다.

  • GC40211 structure
    GC40211Ferrostatin-1 Diyne
    CAS: 2226204-90-4
    Purity: >98.00%

    Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1.

  • GC40226 structure
    GC40226Curcumin-d6
    CAS: 1335198-02-1
    Purity: >99.00%

    커큐민 D6(디페룰로일메탄 D6)은 커큐민(강황 황색)이라고 표시된 중수소입니다.

  • GC40228 structure
    GC40228Fluvastatin-d6 (sodium salt)
    Purity: >95.00%

    Fluvastatin-d6 is intended for use as an internal standard for the quantification of fluvastatin by GC- or LC-MS.

  • GC40922 structure
    GC40922SRS11-92
    CAS: 1467047-25-1
    Purity: >98.00%

    Ferrostatin-1(Fer-1) 유사체인 SRS11-92는 강력한 ferroptosis 억제제입니다.

  • GC41293 structure
    GC41293Glutathione ethyl ester
    CAS: 92614-59-0
    Purity: >96.00%

    Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides.

  • GC42039 structure
    GC420391-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
    CAS: 154436-51-8
    Purity: >98.00%

    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.

  • GC42040 structure
    GC420401-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE
    CAS: 947381-58-0
    Purity: >98.00%

    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.

  • GC42041 structure
    GC420411-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
    CAS: 154436-48-3
    Purity: >98.00%

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.

  • GC42042 structure
    GC420421-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
    CAS: 154436-49-4
    Purity: >90.00%

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.

  • GC42928 structure
    GC42928BHT
    CAS: 128-37-0
    Purity: >99.00%

    BHT는 식품 및 식품 관련 제품에 널리 사용되는 항산화제입니다. BHT는 페롭토시스 억제제입니다.

  • GC43231 structure
    GC43231Cerivastatin (sodium salt)
    CAS: 143201-11-0
    Purity: >98.00%

    세리바스타틴(나트륨염)은 합성 지질 저하제이며, Ki가 1.3nM/L인 매우 강력하고 잘 견디며 경구 활성인 HMG-CoA 환원효소 억제제입니다.

  • GC43297 structure
    GC43297Coenzyme Q2
    CAS: 606-06-4
    Purity: >95.00%

    Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.

  • GC43329 structure
    GC43329Cu-ATSM
    CAS: 68341-09-3
    Purity: >95.00%

    Cu-ATSM은 매우 강력한 라디칼 포획 항산화제(RTA)이자 (인지질)지질 과산화의 억제제이므로 페로프토시스를 억제하는 능력을 설명합니다.

  • GC43623 structure
    GC43623Erastin2
    CAS: 1695533-44-8
    Purity: >98.00%

    Erastin2는 강력한 시스템 xc- 억제제이자 철부활증 유도제이다.

  • GC44214 structure
    GC44214ML-162
    CAS: 1035072-16-2
    Purity: >99.50%

    ML-162는 IC50 값이 1.42μM인 글루타치온 페로다이아제 4(GPX4)를 억제하는 소분자이다.

  • GC44851 structure
    GC44851Rosiglitazone (potassium salt)
    CAS: 316371-84-3
    Purity: >98.00%

    Rosiglitazone(BRL 49653) 칼륨은 경구 활성 선택적 PPARγ입니다. 작용제(EC50: 60nM, Kd: 40nM).

  • GC44893 structure
    GC44893Siramesine (fumarate)
    CAS: 163630-79-3
    Purity: >98.00%

    Siramesine is an agonist of the sigma-2 (σ2) receptor (IC50 = 0.19 nM).

  • GC44947 structure
    GC44947SRS16-86
    CAS: 1793052-96-6
    Purity: >98.00%

    SRS16-86은 세 번째 세대의 철사망 억제제로 펠로스틴 계열에 속한다.

  • GC45248 structure
    GC45248(-)-FINO2
    CAS: 869298-31-7
    Purity: >98.00%

    (-)-FINO2는 선택적으로 철사망을 유도할 수 있는 유기 과산화물이고 철사망과 항암 치료의 기전을 연구하기 위해 사용된다.

  • GC45764 structure
    GC45764Ciclopirox-d11 (sodium salt)
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC45792 structure
    GC45792Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
    CAS: 39916-28-4
    Purity: >95.00%

    An inducer of ferroptosis