GLPBio

Ferroptosis

Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.

Products Related to Ferroptosis(211)

  • GC45793 structure
    GC45793IM-93
    CAS: 1173657-73-2
    Purity: >98.00%

    IM-93은 세포 사멸 억제에 대해 0.45μM의 IC50으로 ferroptosis와 NETosis를 억제합니다.

  • GC45820 structure
    GC45820Balsalazide-d4
    Purity: >99.00%

    Balsalazide-d4는 Balsalazide로 표시된 중수소입니다.

  • GC45928 structure
    GC45928iFSP1
    CAS: 150651-39-1
    Purity: >99.50%

    iFSP1은 글루타티온 비의존 철사 억제 단백질1(FSP1)의 강력한 억제제로 EC 50 값이 103nM이다.

  • GC45995 structure
    GC45995DO264
    CAS: 2301866-59-9
    Purity: >98.50%

    An ABHD12 inhibitor

  • GC46352 structure
    GC46352(S)-DO271
    CAS: 2301865-01-8
    Purity: >98.00%

    An inactive control for DO264

  • GC47065 structure
    GC47065CAY10773
    CAS: 1648546-79-5
    Purity: >98.00%

    A derivative of sorafenib

  • GC47123 structure
    GC47123Coumarin-Quinone Conjugate
    CAS: 2741190-31-6
    Purity: >95.00%

    A fluorescent substrate for NADH:ubiquinone oxidoreductases

  • GC47477 structure
    GC47477JKE-1674
    CAS: 2421119-60-8
    Purity: >98.00%

    JKE-1674는 경구 활성 글루타티온 퍼옥시다제 4(GPX4) 억제제이자 GPX4 억제제 ML-210의 활성 대사 산물입니다. JKE-1674, 니트로이속사졸 고리가 α-니트로케톡심으로 대체된 ML-210의 유사체. JKE-1674는 니트릴 산화물 JKE-1777로 변환할 수 있습니다. JKE-1674는 ML-210과 동일한 방식으로 LOX-IMVI 세포를 죽이고 ferroptosis 억제제에 의해 완전히 구제됩니다.

  • GC47478 structure
    GC47478JKE-1716
    CAS: 2421118-05-8
    Purity: >98.00%

    JKE-1716은 강력하고 선택적인 니트로산 함유 GPX4 억제제입니다.

  • GC47870 structure
    GC47870Pantothenate Kinase Inhibitor
    CAS: 902614-04-4
    Purity: >95.00%

    A reversible inhibitor of pantothenate kinase

  • GC48029 structure
    GC48029RC363
    CAS: 2584411-86-7
    Purity: >98.00%

    An inhibitor of ferroptosis

  • GC48030 structure
    GC48030RC574
    CAS: 2584411-87-8
    Purity: >98.00%

    An inhibitor of ferroptosis

  • GC48059 structure
    GC48059Rosiglitazone-d3
    CAS: 1132641-22-5
    Purity: >99.00%

    An internal standard for the quantification of rosiglitazone

  • GC48650 structure
    GC48650DTUN
    Purity: >95.00%

    A lipophilic hyponitrite radical initiator

  • GC48954 structure
    GC48954CP21
    CAS: 30652-12-1
    Purity: >98.00%

    An iron chelator

  • GC49034 structure
    GC490341(R)-(Trifluoromethyl)oleyl alcohol
    CAS: 2644636-20-2
    Purity: >95.00%

    An oleic acid analog

  • GC49058 structure
    GC49058Pentetic acid (DTPA)
    CAS: 67-43-6
    Purity: >98.00%

    Pentetic acid (DTPA)은 강력한 아미노폴리카복실산 킬레이트제로 EDTA와 유사한 구조를 가지고 있다.

  • GC49308 structure
    GC49308Ungeremine
    CAS: 2121-12-2
    Purity: >98.00%

    A betaine-type alkaloid with diverse biological activities

  • GC49454 structure
    GC49454Complex 3
    CAS: 2480150-28-3
    Purity: >90.00%

    A fluorescent copper complex with anticancer activity

  • GC49560 structure
    GC49560L6H21
    CAS: 24533-47-9
    Purity: >98.00%

    Chalcone 유도체인 L6H21은 경구 활성, 강력하고 특이적인 골수 분화 2(MD-2) 억제제입니다.

  • GC49691 structure
    GC49691PSP
    CAS: 3030735-86-2
    Purity: >98.00%

    A two-photon fluorescent probe for H 2 S n

  • GC49730 structure
    GC497301-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11
    Purity: >99.00%

    An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE- sn -glycero-3-PE

  • GC49868 structure
    GC49868D-α-Tocopheryl Quinone
    CAS: 7559-04-8
    Purity: >98.00%

    An oxidative metabolite of vitamin E

  • GC50345 structure
    GC50345Liproxstatin-1 hydrochloride
    CAS: 2250025-95-5
    Purity: >98%

    Liproxstatin-1 염산염은 강력한 ferroptosis 억제제이며 ferroptosis 세포 사멸을 억제합니다(IC50=22nM).