iFSP1 |
| Catalog No.GC45928 |
AIFM2/FSP1의 억제제
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 150651-39-1
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
iFSP1 is an inhibitor of apoptosis inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1).[1] It decreases cell viability in wild-type, but not glutathione peroxidase 4 (GPX4) knock-out, Pfa1 and HT1080 cells overexpressing AIFM2/FSP1, an effect that can be blocked by the ferroptosis inhibitor liproxstatin-1 . iFSP1 (3 μM) sensitizes a variety of human cancer cell lines to the ferroptosis inducer (1S,3R)-RSL3 .
References:
[1].Doll, S., Freitas, F.P., Shah, R., et al. FSP1 is a glutathione-independent ferroptosis suppressor. Nature (2019).
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *