Home>>Thromboxane B2
Thromboxane B2 Catalog No.GC40536

A quantitative analytical standard guaranteed to meet MaxSpec? identity, purity, stability, and concentration specifications

Size Price Stock Qty
1mg
$75.00
In stock
5mg
$339.00
In stock
10mg
$603.00
In stock

Customer Review

Based on customer reviews.

Tel: (626) 353-8530 Email: [email protected]

Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

View current batch:

Chemical Properties

Cas No. 54397-85-2 SDF Download SDF
Synonyms TXB2
Chemical Name 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid
Canonical SMILES O[[email protected]@H]1[[email protected]](C/C=C\CCCC(O)=O)[[email protected]@H](/C=C/[[email protected]@H](O)CCCCC)OC(O)C1
Formula C20H34O6 M.Wt 370.5
Solubility 10mg/mL in methylacetate, 100mg/mL in ethanol Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
  • Molarity Calculator

  • Dilution Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

Background

TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds.[1] Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.[2],[3],[4]

Reference:
[1]. Needleman, P., Moncada, S., Bunting, S., et al. Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature 261(5561), 558-560 (1976).
[2]. Patrono, C., Ciabattoni, G., Patrignani, P., et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. Adv. Prostaglandin Thromboxane Leukot. Res. 11, 493-498 (1983).
[3]. Lawson, J.A., Patrono, C., Ciabattoni, G., et al. Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. Anal. Biochem. 155(1), 198-205 (1986).
[4]. Patrono, C., Ciabattoni, G., Pugliese, F., et al. Estimated rate of thromboxane secretion into the circulation of normal humans. J. Clin. Invest. 77(2), 590-594 (1986).