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amyloid P-IN-1

Catalog No.GC33160

amyloid P-IN-1 Chemical Structure

Size Price Stock Qty
10mM*1mLinDMSO
$121.00
In stock
1mg
$46.00
In stock
5mg
$83.00
In stock
10mg
$139.00
In stock
50mg
$417.00
In stock
100mg
$695.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Background

pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.

[1]. PCT Int. Appl. (2015), WO 2015165833 A1 20151105. [2]. U.S. Pat. Appl. Publ. (2016), US 20160081983 A1 20160324.

Chemical Properties

Cas No. 1819986-22-5 SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES O=C(OCOC(OC1CCOCC1)=O)[C@H]2CCCN2C(CCCCC(N3[C@@H](C(OCOC(OC4CCOCC4)=O)=O)CCC3)=O)=O
Formula C30H44N2O14 M.Wt 656.68
Solubility DMSO : ≥ 34 mg/mL (51.78 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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