COX
COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.
Products Related to COX(306)
- GN10039RutaecarpineCAS: 84-26-4Purity: >98.00%
Rutaecarpine is an indolopyridoquinazoline alkaloid isolated from Evodia rutaecarpa and known to inhibit COX-2 with an IC 50 of 0.28μM at the cellular level.
- GN10388Gallic acidCAS: 149-91-7Purity: >99.00%
Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities.
- GN1079920(S)-Ginsenoside Rg3CAS: 14197-60-5Purity: >98.00%
20(S)-Ginsenoside Rg3 is a rare ginsenoside extracted from ginseng (Na + : IC 50 = 32.2±4.5μM; hKv1.4: IC 50 = 32.6±2.2μM).
- GC11090DiclofenacCAS: 15307-86-5Purity: >99.50%
Diclofenac is a potent, non-selective cyclooxygenase (COX) inhibitor, with IC₅₀ values of 4nM and 1.3nM for human COX-1 and COX-2, respectively, in CHO cells, and 5.1μM and 0.84μM for ovine COX-1 and COX-2, respectively.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GN10022 | luteolin-6-C-glucoside | 4261-42-1 | >98.00% | |
| GN10039 | Rutaecarpine | 84-26-4 | >98.00% | |
Rutaecarpine is an indolopyridoquinazoline alkaloid isolated from Evodia rutaecarpa and known to inhibit COX-2 with an IC 50 of 0.28μM at the cellular level. | ||||
| GN10080 | Byakangelicol | 26091-79-2 | >98.00% | |
| GN10220 | Ginsenoside Rb3 | 68406-26-8 | >98.00% | |
| GN10388 | Gallic acid | 149-91-7 | >99.00% | |
Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities. | ||||
| GN10395 | Prim-O-glucosylcimifugin | 80681-45-4 | >98.00% | |
| GN10429 | Neochlorogenic acid | 906-33-2 | >98.00% | |
| GN10430 | D-(-)-Salicin | 138-52-3 | >99.00% | |
| GN10549 | Ginsenoside Rd | 52705-93-8 | >98.00% | |
| GN10605 | (+)-Catechin hydrate | 225937-10-0 | >99.50% | |
| GN10645 | Jaceosidin | 18085-97-7 | >98% | |
| GN10685 | Anemarsaponin B | 139051-27-7 | >98% | |
| GN10799 | 20(S)-Ginsenoside Rg3 | 14197-60-5 | >98.00% | |
20(S)-Ginsenoside Rg3 is a rare ginsenoside extracted from ginseng (Na + : IC 50 = 32.2±4.5μM; hKv1.4: IC 50 = 32.6±2.2μM). | ||||
| GC15179 | Ketorolac | 74103-06-3 | >98% | |
non-selective COX inhibitor | ||||
| GC11090 | Diclofenac | 15307-86-5 | >99.50% | |
Diclofenac is a potent, non-selective cyclooxygenase (COX) inhibitor, with IC₅₀ values of 4nM and 1.3nM for human COX-1 and COX-2, respectively, in CHO cells, and 5.1μM and 0.84μM for ovine COX-1 and COX-2, respectively. | ||||
| GC12917 | Acetaminophen | 103-90-2 | >99.00% | |
A COX inhibitor | ||||
| GC15902 | Aceclofenac | 89796-99-6 | >98.00% | |
non-steroidal anti-inflammatory drug | ||||
| GC18133 | ATB-346 | 1226895-20-0 | >98.00% | |
ATB-346 (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). | ||||