COX
COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.
Products Related to COX(306)
- GC61764Teriflunomide impurity 3CAS: 1011244-72-6Purity: >99.50%
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 ?M.
- GC62830AG-024322CAS: 837364-57-5Purity: >98.50%
AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range. AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation?in vivo. AG-024322 induces cell apoptosis.
- GC63267α-ChaconineCAS: 20562-03-2Purity: >98%
α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level.
- GC63398Rebamipide mofetilCAS: 1527495-76-6Purity: >98%
Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759).
- GC63478OcarocoxibCAS: 215122-22-8Purity: >98%
Ocarocoxib, a potent COX-?2 (cyclooxygenase-?2) inhibitor, is a non-steroidal anti-inflammatory for veterinary use.
- GC63804EnflicoxibCAS: 251442-94-1Purity: >99.00%
Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2).
- GC64025TazofeloneCAS: 107902-67-0Purity: >98.00%
Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease.
- GC64032Salicylic acid-d6CAS: 285979-87-5Purity: >99.50%
Salicylic acid-D6 (2-Hydroxybenzoic acid-D6) is a deuterium labeled Salicylic acid.
- GC64136Desmethyl Naproxen-d3CAS: 1189427-82-4Purity: >98.00%
Desmethyl Naproxen-d3 is deuterium labeled Desmethyl Naproxen.
- GC64495Flurbiprofen axetilCAS: 91503-79-6Purity: >99.00%
Flurbiprofen axetil is a non-selective cyclooxygenase (COX) inhibitor.
- GC64804(S)-(+)-Ibuprofen D3CAS: 1329643-44-8Purity: >98%
(S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) is a deuterium labeled (S)-(+)-Ibuprofen.
- GC65519Ibuprofen Impurity FCAS: 65322-85-2Purity: >97.00%
Ibuprofen Impurity F is an Ibuprofen impurity.
- GC66211Ibuprofen sodiumCAS: 31121-93-4Purity: >99.00%
Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
- GC66258PropacetamolCAS: 66532-85-2Purity: >98.00%
Propacetamol is an analgesic agent. Propacetamol also is a precursor form of paracetamol. Propacetamol can be used in postoperative pain, acute trauma and gastrointestinal disorders.
- GC66429Phenacetin-d5CAS: 69323-74-6Purity: >98.00%
Phenacetin-d5 (Acetophenetidin-d5) is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC61764 | Teriflunomide impurity 3 | 1011244-72-6 | >99.50% | |
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 ?M. | ||||
| GC61843 | Mofezolac | 78967-07-4 | >98.50% | |
Mofezolac, a non-steroidal anti-inflammatory drug (NSAID), is a selective, reversible and orally active COX-1 inhibitor with an IC50 of 1.44 nM. | ||||
| GC62830 | AG-024322 | 837364-57-5 | >98.50% | |
AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range. AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation?in vivo. AG-024322 induces cell apoptosis. | ||||
| GC63267 | α-Chaconine | 20562-03-2 | >98% | |
α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level. | ||||
| GC63398 | Rebamipide mofetil | 1527495-76-6 | >98% | |
Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759). | ||||
| GC63478 | Ocarocoxib | 215122-22-8 | >98% | |
Ocarocoxib, a potent COX-?2 (cyclooxygenase-?2) inhibitor, is a non-steroidal anti-inflammatory for veterinary use. | ||||
| GC63683 | Aspirin-d3 | 921943-73-9 | >98% | |
| GC63804 | Enflicoxib | 251442-94-1 | >99.00% | |
Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2). | ||||
| GC64025 | Tazofelone | 107902-67-0 | >98.00% | |
Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease. | ||||
| GC64032 | Salicylic acid-d6 | 285979-87-5 | >99.50% | |
Salicylic acid-D6 (2-Hydroxybenzoic acid-D6) is a deuterium labeled Salicylic acid. | ||||
| GC64136 | Desmethyl Naproxen-d3 | 1189427-82-4 | >98.00% | |
Desmethyl Naproxen-d3 is deuterium labeled Desmethyl Naproxen. | ||||
| GC64137 | Acetaminophen-d3 | 60902-28-5 | >98% | |
| GC64495 | Flurbiprofen axetil | 91503-79-6 | >99.00% | |
Flurbiprofen axetil is a non-selective cyclooxygenase (COX) inhibitor. | ||||
| GC64804 | (S)-(+)-Ibuprofen D3 | 1329643-44-8 | >98% | |
(S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) is a deuterium labeled (S)-(+)-Ibuprofen. | ||||
| GC64833 | Humulone | 26472-41-3 | >98.00% | |
Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. | ||||
| GC64940 | Sudoxicam | 34042-85-8 | >99.00% | |
Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. | ||||
| GC65108 | Phenylbutazone(diphenyl-d10) | 1219794-69-0 | >98.00% | |
| GC65519 | Ibuprofen Impurity F | 65322-85-2 | >97.00% | |
Ibuprofen Impurity F is an Ibuprofen impurity. | ||||
| GC66211 | Ibuprofen sodium | 31121-93-4 | >99.00% | |
Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers. | ||||
| GC66258 | Propacetamol | 66532-85-2 | >98.00% | |
Propacetamol is an analgesic agent. Propacetamol also is a precursor form of paracetamol. Propacetamol can be used in postoperative pain, acute trauma and gastrointestinal disorders. | ||||
| GC66429 | Phenacetin-d5 | 69323-74-6 | >98.00% | |
Phenacetin-d5 (Acetophenetidin-d5) is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats. | ||||
| GC68016 | COX-2-IN-6 | 2756347-91-6 | >98% | |
| GC68323 | Flurbiprofen-d5 | 215175-76-1 | >99.00% | |
| GC68423 | Indomethacin-d4 Methyl Ester | 1217064-61-3 | >98% | |