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COX

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. Product Name Information
  2. GC63267 α-​Chaconine α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level.  α-​Chaconine  Chemical Structure
  3. GC40262 α-Humulene α-Humulene is a sesquiterpene that has been found in C. α-Humulene  Chemical Structure
  4. GC10873 α-Spinasterol TRPV1 antagonist α-Spinasterol  Chemical Structure
  5. GC41623 β-Elemonic Acid β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. β-Elemonic Acid  Chemical Structure
  6. GC41658 (±)-2-hydroxy Ibuprofen (±)-2-hydroxy Ibuprofen is a metabolite of ibuprofen . (±)-2-hydroxy Ibuprofen  Chemical Structure
  7. GC46290 (±)-Ibuprofen-d3 An Analytical Reference Standard (±)-Ibuprofen-d3  Chemical Structure
  8. GC49515 (±)-Ibuprofen-d3 (sodium salt) An internal standard for the quantification of (±)-ibuprofen (±)-Ibuprofen-d3 (sodium salt)  Chemical Structure
  9. GC45278 (±)-Ketoprofen-d3   (±)-Ketoprofen-d3  Chemical Structure
  10. GN10605 (+)-Catechin hydrate (+)-Catechin hydrate  Chemical Structure
  11. GC11049 (+/-)-Sulfinpyrazone platelet COX inhibitor (+/-)-Sulfinpyrazone  Chemical Structure
  12. GC40842 (-)-Catechin (-)-Catechin  Chemical Structure
  13. GC32957 (-)-Catechin gallate ((-)-Catechin 3-gallate) (-)-Catechin gallate ((-)-Catechin 3-gallate) is a minor constituent in green tea catechins. (-)-Catechin gallate ((-)-Catechin 3-gallate) inhibits the activity of COX-1 and COX-2 enzymes. (-)-Catechin gallate ((-)-Catechin 3-gallate)  Chemical Structure
  14. GC10603 (-)-epicatechin gallate major catechin in green tea (-)-epicatechin gallate  Chemical Structure
  15. GC13114 (S)-(+)-Ibuprofen COX inhibitor (S)-(+)-Ibuprofen  Chemical Structure
  16. GC64804 (S)-(+)-Ibuprofen D3 (S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen D3  Chemical Structure
  17. GC18022 (S)-Flurbiprofen inhibitors of COX-1 and COX-2 (S)-Flurbiprofen  Chemical Structure
  18. GC15977 (S)-Ketoprofen COX-1 and COX-2 inhibitor (S)-Ketoprofen  Chemical Structure
  19. GC41389 (S)-Ketorolac (S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac  Chemical Structure
  20. GC14820 (S)-Naproxen (S)-Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. (S)-Naproxen  Chemical Structure
  21. GC49179 (S)-O-Desmethyl Naproxen A metabolite of (S)-naproxen (S)-O-Desmethyl Naproxen  Chemical Structure
  22. GC41761 1-(6-Methoxy-2-naphthyl)ethanol 1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen. 1-(6-Methoxy-2-naphthyl)ethanol  Chemical Structure
  23. GC60447 1-Hydroxy-ibuprofen 1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P. 1-Hydroxy-ibuprofen  Chemical Structure
  24. GC49366 1-Salicylate Glucuronide A metabolite of salicylic acid and aspirin 1-Salicylate Glucuronide  Chemical Structure
  25. GC42201 3,3'-Diiodo-L-thyronine 3,3'-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3'-T2. 3,3'-Diiodo-L-thyronine  Chemical Structure
  26. GC39307 4-Methylamino antipyrine 4-Methylamino antipyrine is an active metabolite of Metamizole. 4-Methylamino antipyrine  Chemical Structure
  27. GC60523 4-Methylamino antipyrine hydrochloride An active metabolite of metamizole 4-Methylamino antipyrine hydrochloride  Chemical Structure
  28. GC49119 5-hydroxy Flunixin A metabolite of flunixin 5-hydroxy Flunixin  Chemical Structure
  29. GC49315 5-hydroxy Indomethacin A metabolite of indomethacin 5-hydroxy Indomethacin  Chemical Structure
  30. GC49183 6-hydroxy Etodolac A metabolite of etodolac 6-hydroxy Etodolac  Chemical Structure
  31. GC16153 6-methoxy Naphthalene Acetic Acid competitive, non-selective COX inhibitor 6-methoxy Naphthalene Acetic Acid  Chemical Structure
  32. GC15338 8,11,14-Eicosatriynoic Acid A Cox, 12-LO, and 5-LO inhibitor 8,11,14-Eicosatriynoic Acid  Chemical Structure
  33. GC14302 9,12-Octadecadiynoic Acid 9,12-Octadecadiynoic Acid (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. 9,12-Octadecadiynoic Acid  Chemical Structure
  34. GC15902 Aceclofenac non-steroidal anti-inflammatory drug Aceclofenac  Chemical Structure
  35. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester  Chemical Structure
  36. GC42692 Aceclofenac methyl ester A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester  Chemical Structure
  37. GC10454 Acemetacin COX inhibitor Acemetacin  Chemical Structure
  38. GC12917 Acetaminophen

    A COX inhibitor

    Acetaminophen  Chemical Structure
  39. GC64137 Acetaminophen-d3 Acetaminophen-d3  Chemical Structure
  40. GC46781 Acetaminophen-d4 A Certified Reference Material Acetaminophen-d4  Chemical Structure
  41. GC31693 Adelmidrol Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ. Adelmidrol  Chemical Structure
  42. GC62830 AG-024322 AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range. AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation?in vivo. AG-024322 induces cell apoptosis. AG-024322  Chemical Structure
  43. GC61689 Alminoprofen Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. Alminoprofen  Chemical Structure
  44. GC14740 Amfenac Sodium Monohydrate Amfenac Sodium Monohydrate is a COX-2 inhibitor. Amfenac Sodium Monohydrate  Chemical Structure
  45. GC14104 Ampiroxicam COX inhibitor Ampiroxicam  Chemical Structure
  46. GC33484 Ampyrone (4-Aminoantipyrine) Ampyrone (4-Aminoantipyrine)  Chemical Structure
  47. GN10685 Anemarsaponin B Anemarsaponin B  Chemical Structure
  48. GC17776 Asaraldehyde COX inhibitor Asaraldehyde  Chemical Structure
  49. GC15706 Aspirin (Acetylsalicylic acid) A non-selective, irreversible COX inhibitor Aspirin (Acetylsalicylic acid)  Chemical Structure
  50. GC63683 Aspirin-d3 Aspirin-d3  Chemical Structure
  51. GC42859 Aspirin-d4 Aspirin-d4 is intended for use as an internal standard for the quantification of aspirin by GC- or LC-MS. Aspirin-d4  Chemical Structure
  52. GC18133 ATB-346 ATB-346 (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). ATB-346  Chemical Structure
  53. GC35493 Benzoylgomisin O Benzoylgomisin O isolated from Schisandra rubriflora, has inhibitory activity against 15-LOX, COX-1 and COX-2 enzymes and anti-inflammatory activity. Benzoylgomisin O  Chemical Structure
  54. GC13039 Bromfenac Sodium COX inhibitor Bromfenac Sodium  Chemical Structure
  55. GC15410 Bufexamac COX inhibitor Bufexamac  Chemical Structure
  56. GN10080 Byakangelicol Byakangelicol  Chemical Structure
  57. GC40352 Cafestol Cafestol is a natural diterpene which is abundant in unfiltered coffee. Cafestol  Chemical Structure
  58. GC17341 Carprofen COX inhibitor Carprofen  Chemical Structure
  59. GC32841 Catechin ((+)-Catechin) Catechin ((+)-Catechin) ((+)-Catechin ((+)-Catechin)) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Catechin ((+)-Catechin)  Chemical Structure
  60. GC43149 CAY10404

    Many non-steroidal anti-inflammatory drugs (NSAIDs) are potent but non-selective inhibitors of both COX-1 and COX-2 in humans.

    CAY10404  Chemical Structure
  61. GC18427 CAY10452 CAY10452 (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. CAY10452  Chemical Structure
  62. GC14475 Celecoxib Selective cyclooxygenase-2 (COX-2) inhibitor Celecoxib  Chemical Structure
  63. GC49152 Celecoxib Carboxylic Acid An inactive metabolite of celecoxib Celecoxib Carboxylic Acid  Chemical Structure
  64. GC47070 Celecoxib-d7 An internal standard for the quantification of celecoxib Celecoxib-d7  Chemical Structure
  65. GC31707 Chebulagic acid Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid  Chemical Structure
  66. GC18369 Cimicoxib A selective inhibitor of COX-2 Cimicoxib  Chemical Structure
  67. GC31749 Columbin A diterpenoid furanolactone with diverse biological activities Columbin  Chemical Structure
  68. GN10338 Compound K Compound K  Chemical Structure
  69. GC31962 COX-2-IN-1 COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM. COX-2-IN-1  Chemical Structure
  70. GC68016 COX-2-IN-6 COX-2-IN-6  Chemical Structure
  71. GC31967 COX/5-LO-IN-1 COX/5-LO-IN-1 (Atreleuton analog) is an inhibitor of cylooxygenase and 5-lipoxygenase (5-LO), used for the research of inflammatory and allergic disease states. COX/5-LO-IN-1  Chemical Structure
  72. GC32030 COX2-IN-1 COX2-IN-1  Chemical Structure
  73. GC38224 Crocin II Crocin II  Chemical Structure
  74. GN10430 D-(-)-Salicin D-(-)-Salicin  Chemical Structure
  75. GC38184 Dehydrodiisoeugenol Dehydrodiisoeugenol  Chemical Structure
  76. GC38431 Dehydroevodiamine Dehydroevodiamine is a major bioactive quinazoline alkaloid isolated from Evodiae Fructus, has an antiarrhythmic effect in guinea-pig ventricular myocytes. Dehydroevodiamine  Chemical Structure
  77. GC16077 Deracoxib Selective COX-2 inhibitor Deracoxib  Chemical Structure
  78. GC64136 Desmethyl Naproxen-d3 Desmethyl Naproxen-d3 is deuterium labeled Desmethyl Naproxen. Desmethyl Naproxen-d3  Chemical Structure
  79. GC11090 Diclofenac

    non-selective COX inhibitor

    Diclofenac  Chemical Structure
  80. GC47212 Diclofenac amide A prodrug form of diclofenac Diclofenac amide  Chemical Structure
  81. GC14587 Diclofenac Diethylamine non-selective COX inhibitor Diclofenac Diethylamine  Chemical Structure
  82. GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester  Chemical Structure
  83. GC14622 Diclofenac Potassium nonsteroidal anti-inflammatory drug Diclofenac Potassium  Chemical Structure
  84. GC14261 Diclofenac Sodium

    COX inhibitor

    Diclofenac Sodium  Chemical Structure
  85. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4  Chemical Structure
  86. GC12591 Diflunisal

    COX inhibitor, nonsteroidal anti-inflammatory drug (NSAID)

    Diflunisal  Chemical Structure
  87. GC12156 DuP 697 cyclooxygenase-2 inhibitor DuP 697  Chemical Structure
  88. GC38015 Eicosatetraynoic acid A nonspecific inhibitor of cyclooxygenases and lipoxygenases Eicosatetraynoic acid  Chemical Structure
  89. GC12229 Eicosatetraynoic Acid nonspecific inhibitor of cyclooxygenases and lipoxygenases Eicosatetraynoic Acid  Chemical Structure
  90. GC47287 Eltenac A non-selective COX inhibitor Eltenac  Chemical Structure
  91. GC63804 Enflicoxib Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2). Enflicoxib  Chemical Structure
  92. GN10004 EsculentosideA EsculentosideA  Chemical Structure
  93. GC38678 Ethyl Caffeate Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl Caffeate  Chemical Structure
  94. GC43635 Ethyl p-methoxycinnamate Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. Ethyl p-methoxycinnamate  Chemical Structure
  95. GC16662 Etodolac COX-2 inhibitor Etodolac  Chemical Structure
  96. GC49156 Etodolac Acyl Glucuronide A phase II metabolite of etodolac Etodolac Acyl Glucuronide  Chemical Structure
  97. GC10429 Etoricoxib A selective COX-2 inhibitor Etoricoxib  Chemical Structure
  98. GC36014 Etoricoxib D4 Etoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib D4  Chemical Structure
  99. GC13746 Fenbufen COX inhibitor, non-steroidal anti-inflammatory drug Fenbufen  Chemical Structure
  100. GC14584 Fenofibric acid ppar inhibitor, lipid-lowering agent Fenofibric acid  Chemical Structure
  101. GC17882 Fenoprofen Calcium nonsteroidal, anti-inflammatory antiarthritic agent Fenoprofen Calcium  Chemical Structure

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