Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

    image loader

    Adding item(s) to cart......

Home >> Signaling Pathways >> Neuroscience >> COX

COX

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. Product Name Information
  2. GC63267 α-​Chaconine α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level. α-​Chaconine Chemical Structure
  3. GC40262 α-Humulene

    αCaryophyllene, (±)-αHumulene

     α-Humulene is a sesquiterpene that has been found in C. α-Humulene Chemical Structure
  4. GC10873 α-Spinasterol

    Bessisterol, Hitodesterol

     TRPV1 antagonist α-Spinasterol Chemical Structure
  5. GC41623 β-Elemonic Acid

    Elemadienonic Acid, 3-Oxotirucallenoic Acid, 3-oxo Tirucallic Acid

     β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. β-Elemonic Acid Chemical Structure
  6. GC41658 (±)-2-hydroxy Ibuprofen (±)-2-hydroxy Ibuprofen is a metabolite of ibuprofen . (±)-2-hydroxy Ibuprofen Chemical Structure
  7. GC49515 (±)-Ibuprofen-d3 (sodium salt)

    DL-Ibuprofen-d3

     An internal standard for the quantification of (±)-ibuprofen (±)-Ibuprofen-d3 (sodium salt) Chemical Structure
  8. GC45278 (±)-Ketoprofen-d3

    (R,S)-Ketoprofen-d3, 2-(3-benzoylphenyl)Propionic Acid-d3

       (±)-Ketoprofen-d3 Chemical Structure
  9. GN10605 (+)-Catechin hydrate

    D-(+)-Catechin, Catechuic Acid, Cyanidol

     (+)-Catechin hydrate Chemical Structure
  10. GC11049 (+/-)-Sulfinpyrazone

    G-28315, NSC 75925

     platelet COX inhibitor (+/-)-Sulfinpyrazone Chemical Structure
  11. GC40842 (-)-Catechin

    (2S,3R)-Catechin, ent-Catechin, L-Catechin, NSC 81746

     (-)-Catechin Chemical Structure
  12. GC32957 (-)-Catechin gallate ((-)-Catechin 3-gallate)

    (-)-CG

     (-)-Catechin gallate ((-)-Catechin 3-gallate) is a minor constituent in green tea catechins. (-)-Catechin gallate ((-)-Catechin 3-gallate) inhibits the activity of COX-1 and COX-2 enzymes. (-)-Catechin gallate ((-)-Catechin 3-gallate) Chemical Structure
  13. GC10603 (-)-epicatechin gallate

    ECG

     (-)-epicatechin gallate is a natural flavanol belonging to the ester-type catechins in tea polyphenols. (-)-epicatechin gallate exerts anti-inflammatory effects by inhibiting cyclooxygenase-1 (COX-1) with an IC₅₀ of 7.5μM. (-)-epicatechin gallate Chemical Structure
  14. GC13114 (S)-(+)-Ibuprofen

    Dexibuprofen, (+)-Ibuprofen

     COX inhibitor (S)-(+)-Ibuprofen Chemical Structure
  15. GC64804 (S)-(+)-Ibuprofen D3 (S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen D3 Chemical Structure
  16. GC18022 (S)-Flurbiprofen inhibitors of COX-1 and COX-2 (S)-Flurbiprofen Chemical Structure
  17. GC15977 (S)-Ketoprofen

    (S)-2-(3-benzoylphenyl)Propionic Acid,Dexketoprofen

     COX-1 and COX-2 inhibitor (S)-Ketoprofen Chemical Structure
  18. GC41389 (S)-Ketorolac

    (-)-Ketorolac

     (S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac Chemical Structure
  19. GC14820 (S)-Naproxen

    CG 3117, (S)-Naproxen

     (S)-Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. (S)-Naproxen Chemical Structure
  20. GC49179 (S)-O-Desmethyl Naproxen

    (S)-6-Desmethyl Naproxen

     A metabolite of (S)-naproxen (S)-O-Desmethyl Naproxen Chemical Structure
  21. GC41761 1-(6-Methoxy-2-naphthyl)ethanol

    Naproxen Impurity K

     1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen. 1-(6-Methoxy-2-naphthyl)ethanol Chemical Structure
  22. GC60447 1-Hydroxy-ibuprofen 1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P. 1-Hydroxy-ibuprofen Chemical Structure
  23. GC49366 1-Salicylate Glucuronide

    Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide

     A metabolite of salicylic acid and aspirin 1-Salicylate Glucuronide Chemical Structure
  24. GN10799 20(S)-Ginsenoside Rg3

    20(S)-Propanaxadiol

     20(S)-Ginsenoside Rg3 is a rare ginsenoside extracted from ginseng (Na+: IC50 = 32.2±4.5μM; hKv1.4: IC50 = 32.6±2.2μM). 20(S)-Ginsenoside Rg3 Chemical Structure
  25. GC42201 3,3'-Diiodo-L-thyronine

    L-3,3'-Diiodothyronine, T2, 3,3'-T2

     3,3'-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3'-T2. 3,3'-Diiodo-L-thyronine Chemical Structure
  26. GC91680 4-Acetamido Antipyrine

    4-AAAP,NSC 331807

     4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole . 4-Acetamido Antipyrine Chemical Structure
  27. GC39307 4-Methylamino antipyrine 4-Methylamino antipyrine is an active metabolite of Metamizole. 4-Methylamino antipyrine Chemical Structure
  28. GC60523 4-Methylamino antipyrine hydrochloride

    Metamizole Impurity C

     An active metabolite of metamizole 4-Methylamino antipyrine hydrochloride Chemical Structure
  29. GC90889 5-(3'-Hydroxyphenyl)-γ-Valerolactone

    A metabolite of various polyphenols

     5-(3'-Hydroxyphenyl)-γ-Valerolactone Chemical Structure
  30. GC49119 5-hydroxy Flunixin A metabolite of flunixin 5-hydroxy Flunixin Chemical Structure
  31. GC49315 5-hydroxy Indomethacin

    O-Desmethyl Indomethacin

     A metabolite of indomethacin 5-hydroxy Indomethacin Chemical Structure
  32. GC49183 6-hydroxy Etodolac A metabolite of etodolac 6-hydroxy Etodolac Chemical Structure
  33. GC16153 6-methoxy Naphthalene Acetic Acid

    6-MNA

     competitive, non-selective COX inhibitor 6-methoxy Naphthalene Acetic Acid Chemical Structure
  34. GC15338 8,11,14-Eicosatriynoic Acid

    8,11,14-ETI

     A Cox, 12-LO, and 5-LO inhibitor 8,11,14-Eicosatriynoic Acid Chemical Structure
  35. GC14302 9,12-Octadecadiynoic Acid

    Ro 3-1314

     9,12-Octadecadiynoic Acid (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. 9,12-Octadecadiynoic Acid Chemical Structure
  36. GC15902 Aceclofenac non-steroidal anti-inflammatory drug Aceclofenac Chemical Structure
  37. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester Chemical Structure
  38. GC42692 Aceclofenac methyl ester

    Aceclofenac Impurity D

     A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester Chemical Structure
  39. GC10454 Acemetacin COX inhibitor Acemetacin Chemical Structure
  40. GC12917 Acetaminophen

    4-Acetamidophenol, APAP, 4'-Hydroxyacetanilide, NSC 3991, NSC 109028, Paracetamol

    A COX inhibitor

     Acetaminophen Chemical Structure
  41. GC64137 Acetaminophen-d3 Acetaminophen-d3 Chemical Structure
  42. GC31693 Adelmidrol Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ. Adelmidrol Chemical Structure
  43. GC62830 AG-024322 AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range. AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation?in vivo. AG-024322 induces cell apoptosis. AG-024322 Chemical Structure
  44. GC61689 Alminoprofen Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. Alminoprofen Chemical Structure
  45. GC14740 Amfenac Sodium Monohydrate Amfenac Sodium Monohydrate is a COX-2 inhibitor. Amfenac Sodium Monohydrate Chemical Structure
  46. GC14104 Ampiroxicam

    CP 65,703

     COX inhibitor Ampiroxicam Chemical Structure
  47. GC33484 Ampyrone (4-Aminoantipyrine) Ampyrone (4-Aminoantipyrine) Chemical Structure
  48. GN10685 Anemarsaponin B Anemarsaponin B Chemical Structure
  49. GC17776 Asaraldehyde COX inhibitor Asaraldehyde Chemical Structure
  50. GC15706 Aspirin (Acetylsalicylic acid)

    Acetylsalicylic Acid, NSC 27223, NSC 406186

     A non-selective, irreversible COX inhibitor Aspirin (Acetylsalicylic acid) Chemical Structure
  51. GC63683 Aspirin-d3 Aspirin-d3 Chemical Structure
  52. GC42859 Aspirin-d4

    Acetylsalicylic Acid-d4

     Aspirin-d4 is intended for use as an internal standard for the quantification of aspirin by GC- or LC-MS. Aspirin-d4 Chemical Structure
  53. GC18133 ATB-346

    ATB-346

     ATB-346 (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). ATB-346 Chemical Structure
  54. GC45820 Balsalazide-d4 A neuropeptide with diverse biological activities Balsalazide-d4 Chemical Structure
  55. GC35493 Benzoylgomisin O Benzoylgomisin O isolated from Schisandra rubriflora, has inhibitory activity against 15-LOX, COX-1 and COX-2 enzymes and anti-inflammatory activity. Benzoylgomisin O Chemical Structure
  56. GC13039 Bromfenac Sodium

    AHR 10282B

     COX inhibitor Bromfenac Sodium Chemical Structure
  57. GC15410 Bufexamac COX inhibitor Bufexamac Chemical Structure
  58. GN10080 Byakangelicol Byakangelicol Chemical Structure
  59. GC40352 Cafestol Cafestol, one of the major components of coffee, is a coffee-specific diterpene form and an inhibitor of ERK2. Cafestol Chemical Structure
  60. GC17341 Carprofen

    Carprodyl, NSC 297935

     COX inhibitor Carprofen Chemical Structure
  61. GC32841 Catechin ((+)-Catechin) Catechin ((+)-Catechin) ((+)-Catechin ((+)-Catechin)) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Catechin ((+)-Catechin) Chemical Structure
  62. GC70218 Cavidine Cavidine ((+)-Cavidine) is a selective COX-2 inhibitor which possesses anti-inflammatory activity. Cavidine Chemical Structure
  63. GC43149 CAY10404

    Many non-steroidal anti-inflammatory drugs (NSAIDs) are potent but non-selective inhibitors of both COX-1 and COX-2 in humans.

     CAY10404 Chemical Structure
  64. GC18427 CAY10452

    PTPBS

     CAY10452 (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. CAY10452 Chemical Structure
  65. GC14475 Celecoxib

    SC58635, YM177

     Celecoxib is a highly selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 value of 40nM. Celecoxib Chemical Structure
  66. GC49152 Celecoxib Carboxylic Acid An inactive metabolite of celecoxib Celecoxib Carboxylic Acid Chemical Structure
  67. GC68849 Celecoxib-d3

    SC 58635-d3

    Celecoxib-d3 is the deuterated form of Celecoxib. Celecoxib is a selective COX-2 inhibitor with an IC50 of 40 nM.

     Celecoxib-d3 Chemical Structure
  68. GC47070 Celecoxib-d7 An internal standard for the quantification of celecoxib Celecoxib-d7 Chemical Structure
  69. GC31707 Chebulagic acid Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid Chemical Structure
  70. GC18369 Cimicoxib

    UR8880

     A selective inhibitor of COX-2 Cimicoxib Chemical Structure
  71. GC31749 Columbin A diterpenoid furanolactone with diverse biological activities Columbin Chemical Structure
  72. GC31962 COX-2-IN-1 COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM. COX-2-IN-1 Chemical Structure
  73. GC68016 COX-2-IN-6 COX-2-IN-6 Chemical Structure
  74. GC31967 COX/5-LO-IN-1

    Atreleuton analog

     COX/5-LO-IN-1 (Atreleuton analog) is an inhibitor of cylooxygenase and 5-lipoxygenase (5-LO), used for the research of inflammatory and allergic disease states. COX/5-LO-IN-1 Chemical Structure
  75. GC32030 COX2-IN-1 COX2-IN-1 Chemical Structure
  76. GC38224 Crocin II Crocin II Chemical Structure
  77. GN10430 D-(-)-Salicin

    NSC 5751, D-(-)-Salicin

     D-(-)-Salicin Chemical Structure
  78. GC38184 Dehydrodiisoeugenol Dehydrodiisoeugenol (DEH) is a representative and major benzofuran-type neolignan found in Myristica fragrans Houtt, possessing antibacterial, anti-inflammatory, anticancer, and antioxidant properties. Dehydrodiisoeugenol Chemical Structure
  79. GC38431 Dehydroevodiamine Dehydroevodiamine is a major bioactive quinazoline alkaloid isolated from Evodiae Fructus, has an antiarrhythmic effect in guinea-pig ventricular myocytes. Dehydroevodiamine Chemical Structure
  80. GC16077 Deracoxib

    SC-59046

     Selective COX-2 inhibitor Deracoxib Chemical Structure
  81. GC64136 Desmethyl Naproxen-d3 Desmethyl Naproxen-d3 is deuterium labeled Desmethyl Naproxen. Desmethyl Naproxen-d3 Chemical Structure
  82. GC11090 Diclofenac Diclofenac is a potent, non-selective cyclooxygenase (COX) inhibitor, with IC₅₀ values of 4nM and 1.3nM for human COX-1 and COX-2, respectively, in CHO cells, and 5.1μM and 0.84μM for ovine COX-1 and COX-2, respectively. Diclofenac Chemical Structure
  83. GC47212 Diclofenac amide

    Diclofenac Lactam, 1-(2,6-Dichlorophenyl)oxindole, NSC 621845

     A prodrug form of diclofenac Diclofenac amide Chemical Structure
  84. GC14587 Diclofenac Diethylamine non-selective COX inhibitor Diclofenac Diethylamine Chemical Structure
  85. GC43447 Diclofenac methyl ester

    Methanol Diclofenac ester

     Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  86. GC14622 Diclofenac Potassium Diclofenac Potassium is a potent, non-selective cyclooxygenase (COX) inhibitor, with IC₅₀ values of 4nM and 1.3nM for human COX-1 and COX-2, respectively, in CHO cells, and 5.1μM and 0.84μM for ovine COX-1 and COX-2, respectively. Diclofenac Potassium Chemical Structure
  87. GC14261 Diclofenac Sodium Diclofenac Sodium is a potent, non-selective cyclooxygenase (COX) inhibitor, with IC₅₀ values of 4nM and 1.3nM for human COX-1 and COX-2, respectively, in CHO cells, and 5.1μM and 0.84μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium Chemical Structure
  88. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4 Chemical Structure
  89. GC12591 Diflunisal

    5-(2,4-Difluorophenyl)salicylic Acid, MK-647

    COX inhibitor, nonsteroidal anti-inflammatory drug (NSAID)

     Diflunisal Chemical Structure
  90. GC12156 DuP 697 cyclooxygenase-2 inhibitor DuP 697 Chemical Structure
  91. GC38015 Eicosatetraynoic acid A nonspecific inhibitor of cyclooxygenases and lipoxygenases Eicosatetraynoic acid Chemical Structure
  92. GC12229 Eicosatetraynoic Acid

    ETYA

     nonspecific inhibitor of cyclooxygenases and lipoxygenases Eicosatetraynoic Acid Chemical Structure
  93. GC47287 Eltenac A non-selective COX inhibitor Eltenac Chemical Structure
  94. GC63804 Enflicoxib

    E 6087

     Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2). Enflicoxib Chemical Structure
  95. GN10004 EsculentosideA EsculentosideA Chemical Structure
  96. GC38678 Ethyl Caffeate Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl Caffeate Chemical Structure
  97. GC43635 Ethyl p-methoxycinnamate

    EPMC, Ethyl 4-methoxycinnamate, Ethyl para-methoxycinnamate

     Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. Ethyl p-methoxycinnamate Chemical Structure
  98. GC16662 Etodolac

    AY 24236, (±)-Etodolac, NIH 9918, NSC 282126

     COX-2 inhibitor Etodolac Chemical Structure
  99. GC49156 Etodolac Acyl Glucuronide A phase II metabolite of etodolac Etodolac Acyl Glucuronide Chemical Structure
  100. GC10429 Etoricoxib

    L-791,456, MK-0663

     Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Etoricoxib inhibits the activity of COX-2 (IC50=1.1μM) and COX-1 (IC50=116μM). Etoricoxib Chemical Structure
  101. GC36014 Etoricoxib D4 Etoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib D4 Chemical Structure

Items 1 to 100 of 295 total

per page
  1. 1
  2. 2
  3. 3

Set Descending Direction