COX

A dual inhibitor of COX and 5-LO

Salicylic Acid-d4 is the deuterium labeled 2-Carboxyphenol.

An internal standard for the quantification of (±)-ibuprofen

A metabolite of indomethacin

Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells.

Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties.

Pentagamavunon-1 (PGV-1), a Curcumin analog with oral activity, targets on several molecular mechanisms to induce apoptosis including inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 inhibits NF-κB activation.

PTUPB is a novel dual COX-2 and sEH inhibitor with IC 50 values of 1.26 nM and 0.9 μM, respectively.

Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells.

1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P.

An active metabolite of metamizole

Ibuprofen impurity 1 is an Ibuprofen impurity.

Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively.

An internal standard for the quantification of ketorolac

An internal standard for the quantification of mefenamic acid

Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis.

An internal standard for the quantification of piroxicam

An internal standard for the quantification of rebamipide

Regaloside B is a phenylpropanoid isolated from Lilium longiflorum.

Rehmapicrogenin, isolated from the root of Rehmannia glutinosa, exhibits potent anti-inflammatory effect by inhibiting iNOS, COX-2 and IL-6.

Tolmetin is an orally active and potent COX inhibitor with IC50s of 0.35 ?M and 0.82 ?M human COX-1 and COX-2, respectively.

Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities.

Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2).

Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class.