GLPBio

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products Related to Dopamine Receptor(300)

  • GC31278 structure
    GC31278BP 897
    CAS: 192384-87-5

    BP 897 is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist.

  • GC31287 structure
    GC31287U91356
    CAS: 152886-85-6
    Purity: >98%

    U91356 is a dopamine receptor agonist.

  • GC31418 structure
    GC31418Clebopride malate
    CAS: 57645-91-7
    Purity: >99.50%

    Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.

  • GC33510 structure
    GC33510Org-10490
    CAS: 83507-02-2
    Purity: >98%

    Org-10490 is an antagonist of dopamine D1 receptor and dopamine D2 receptor, used for the treatment for psychiatric disease.

  • GC33527 structure
    GC33527Trimethobenzamide hydrochloride (Ro 2-9578)
    CAS: 554-92-7
    Purity: >99.50%

    Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor.

  • GC33544 structure
    GC33544(±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)
    CAS: 1189805-51-3
    Purity: >98.00%

    (±)-Levomepromazine D6 ((±)-Methotrimeprazine D6) is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist.

  • GC33552 structure
    GC33552ABT-670
    CAS: 630119-43-6
    Purity: >98%

    ABT-670 is a selective, oral bioavailable agonist of dopamine D4 receptor, with EC50 of 89 nM, 160 nM, and 93 nM for human?D4, ferret?D4, and rat?D4, respectively.

  • GC33664 structure
    GC33664SKF-82958 hydrobromide ((±)-SKF 82958 hydrobromide)
    CAS: 74115-01-8
    Purity: >99.50%

    SKF-82958 ((±)-SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM).

  • GC33727 structure
    GC33727SKF 82958 ((±)-SKF 82958)
    CAS: 80751-65-1
    Purity: >98%

    SKF 82958 ((±)-SKF 82958) ((±)-SKF 82958) is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM).

  • GC33730 structure
    GC33730Pentiapine (CGS 10746)
    CAS: 81382-51-6
    Purity: >99.50%

    Pentiapine (CGS 10746) (CGS 10746) is a dopamine release inhibitor without binding to synaptic dopamine receptor sites.

  • GC34949 structure
    GC34949(-)-Isocorypalmine
    CAS: 483-34-1
    Purity: >98.50%

    An isoquinoline alkaloid and metabolite of L-THP with diverse biological activities

  • GC35252 structure
    GC35252Adoprazine
    CAS: 222551-17-9
    Purity: >98.00%

    Adoprazine (SLV313) is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors.

  • GC35323 structure
    GC35323Amisulpride hydrochloride
    CAS: 81342-13-4
    Purity: >98%

    Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.

  • GC35492 structure
    GC35492Benzamide Derivative 1
    CAS: 108226-05-7
    Purity: >98%

    Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18.

  • GC35610 structure
    GC35610Cariprazine hydrochloride
    CAS: 1083076-69-0
    Purity: >98.50%

    An atypical antipsychotic

  • GC35847 structure
    GC35847Dexpramipexole
    CAS: 104632-28-2
    Purity: >98%

    Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist.

  • GC35848 structure
    GC35848Dexpramipexole dihydrochloride
    CAS: 104632-27-1
    Purity: >99.50%

    An anti-apoptotic antioxidant

  • GC35864 structure
    GC35864Dihydrexidine
    CAS: 123039-93-0
    Purity: >98%

    Dihydrexidine (DAR-0100) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM for D1 receptor.

  • GC36069 structure
    GC36069Foscarbidopa
    CAS: 1907685-81-7
    Purity: >98%

    Foscarbidopa (Carbidopa 4′-monophosphate) is a prodrug of Carbidopa, acts as a dopamine receptor agonist.

  • GC36209 structure
    GC36209Haloperidol D4
    CAS: 1189986-59-1
    Purity: >98%

    Haloperidol D4 is deuterium labeled haloperidol, and the latter is a potent dopamine D2 receptor antagonist.

  • GC36370 structure
    GC36370JNJ-37822681 dihydrochloride
    CAS: 2108806-02-4
    Purity: >98.00%

    JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.

  • GC36602 structure
    GC36602Metoclopramide hydrochloride hydrate
    CAS: 54143-57-6
    Purity: >99.50%
  • GC36726 structure
    GC36726Neuromedin N
    CAS: 92169-45-4
    Purity: >99.00%

    Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.

  • GC36875 structure
    GC36875Perphenazine D8 Dihydrochloride
    Purity: >98%

    Perphenazine D8 Dihydrochloride is the deuterium labeled Perphenazine, which is a typical antipsychotic drug(5-HT, Dopamine receptor ligand).