GLPBio

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products Related to Dopamine Receptor(300)

  • GC36924 structure
    GC36924Pipamperone
    CAS: 1893-33-0
    Purity: >99.50%

    Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7).

  • GC36929 structure
    GC36929Piribedil
    CAS: 3605-01-4
    Purity: >99.50%

    A dopamine receptor agonist

  • GC37055 structure
    GC37055Quetiapine D4 fumarate
    CAS: 1287376-15-1
    Purity: >98%

    Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate.

  • GC37067 structure
    GC37067rac-Rotigotine Hydrochloride
    CAS: 102120-99-0
    Purity: >98.50%

    rac-Rotigotine Hydrochloride is a racemate of Rotigotine.

  • GC37539 structure
    GC37539Risperidone hydrochloride
    CAS: 666179-74-4
    Purity: >98%

    Risperidone hydrochloride (R 64 766 hydrochloride) 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.

  • GC37540 structure
    GC37540Risperidone mesylate
    CAS: 666179-96-0
    Purity: >98%

    Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.

  • GC37562 structure
    GC37562Rotigotine D7 Hydrochloride
    Purity: >98%

    Rotigotine (N-0923) D7 Hydrochloride is the deuterium labeled Rotigotine(N-0923), which is a dopamine D2 and D3 receptor agonist.

  • GC37598 structure
    GC37598SB269652
    CAS: 215802-15-6
    Purity: >98.50%

    SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R); a new chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology.

  • GC37600 structure
    GC37600SB-277011
    CAS: 215803-78-4
    Purity: >98.50%

    SB-277011 is a potent and delective dopamine D3 receptor antagonist (pKi values are 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively); brain penetrant.

  • GC37684 structure
    GC37684ST-836
    CAS: 1148156-63-1
    Purity: >98%

    ST-836 is a dopamine receptor ligand; Antiparkinsonian agent.

  • GC37685 structure
    GC37685ST-836 hydrochloride
    CAS: 1415564-68-9
    Purity: >98.00%

    ST-836 hydrochloride (compound 34) is a potent dopamine receptor ligand with Ki values of 4.5 nM, 132 nM for D3 and D2, respectively.

  • GC37702 structure
    GC37702Sumanirole maleate
    CAS: 179386-44-8
    Purity: >98.00%

    A dopamine D 2 receptor agonist

  • GC37729 structure
    GC37729Talipexole
    CAS: 101626-70-4
    Purity: >98%

    Talipexole (B-HT920) is a dopamine agonist that has been proposed as an antiparkinsonian agent.

  • GC37969 structure
    GC37969Ziprasidone D8
    CAS: 1126745-58-1
    Purity: >98%

    Ziprasidone D8 is deuterium labeled Ziprasidone, which is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.

  • GC38022 structure
    GC38022GR 103691
    CAS: 162408-66-4
    Purity: >98%
  • GC38228 structure
    GC38228D-Tetrahydropalmatine
    CAS: 3520-14-7
    Purity: >98.00%

    D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis.

  • GC38231 structure
    GC38231Pericyazine
    CAS: 2622-26-6
    Purity: >99.50%

    A typical antipsychotic

  • GC38405 structure
    GC38405Odapipam
    CAS: 131796-63-9
    Purity: >99.00%

    Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D1 receptor antagonist with a Kd of 0.18 nM.

  • GC38521 structure
    GC38521Carmoxirole hydrochloride
    CAS: 115092-85-8
    Purity: >98%
  • GC38805 structure
    GC38805L-745870
    CAS: 158985-00-3
    Purity: >98%

    L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM.

  • GC38806 structure
    GC38806L-745870 hydrochloride
    CAS: 1173023-36-3
    Purity: >99.50%

    L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM.

  • GC38935 structure
    GC38935ONC206
    CAS: 1638178-87-6
    Purity: >99.00%

    ONC206 is a dopamine D2-like receptor (DRD2/3/4) antagonist belonging to the imipridone class of drugs, with an IC 50 of 0.21μM to 0.32μM.

  • GC39184 structure
    GC39184Solriamfetol
    CAS: 178429-62-4
    Purity: >98.00%
  • GC39192 structure
    GC39192Fluphenazine decanoate
    CAS: 5002-47-1
    Purity: >99.00%

    Fluphenazine decanoate is a dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic.