Pain Research

A synthetic peptide derivative of somatostatin

A metabolite of bradykinin

A CGRP receptor antagonist

A hypothalamic neuropeptide

JNJ-42226314 is a competitive, highly selective and reversible non-covalent monoacylglycerol lipase (MAGL) inhibitor.

PTUPB is a novel dual COX-2 and sEH inhibitor with IC 50 values of 1.26 nM and 0.9 μM, respectively.

Mofezolac, a non-steroidal anti-inflammatory drug (NSAID), is a selective, reversible and orally active COX-1 inhibitor with an IC50 of 1.44 nM.

7-Hydroxyflavone is a flavonoid isolated from M.

An antagonist of calcitonin and amylin receptors

A potential impurity in commercial preparations of naloxone

A synthetic peptide and nociceptin receptor antagonist

An inhibitor of the Ca v 2.2-CRMP2 protein-protein interaction

A derivative of ATP and an antagonist of the purinergic P2Y 1 , P2X 3 , and P2X 2/3 receptors

An internal standard for the quantification of propoxur

An internal standard for the quantification of mepivacaine

An alkaloid and a μ-opioid receptor partial agonist and κ-opioid receptor agonist

A metabolite of doxepin

Chlorphenesin carbamate is a muscle relaxant.

Promethazine sulfoxide is a metabolite of the histamine H1 receptor antagonist promethazine .

Proxymetacaine is an anesthetic.

4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .

Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .

TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).

Methyl salicylate-d4 is intended for use as an internal standard for the quantification of methyl salicylate by GC- or LC-MS.