Innate Immunity

PDIC-NS is an activator of stimulator of interferon genes (STING).

DSPE-PEG(2000)-mannose has been used in the generation of liposomes and mixed micelles for the delivery of anticancer agents to tumor-associated macrophages (TAMs) in vitro and in vivo.

Rhein-13C6 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS.

E17241 is an inducer of the expression of ABCA1, the gene encoding ATP-binding cassette transporter 1; subfamily A (ABCA1).

Phytantriol is an aliphatic alcohol that has been used in the formation of liquid crystalline nanoparticles (LCNPs) and cubosomes.

LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4; IC50 = 0.38 ?M).

Calcium influx inducer compound 634 is an inducer of calcium influx.

DPTIP is an inhibitor of neutral sphingomyelinase 2 (nSMase2; IC50 = 30 nM).

N,N′-Diferuloylputrescine is a polyamine that has been found in Z. mays and has diverse biological activities.

Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that has been used in the generation of supramolecular lipid nanoparticles (SMLNPs) encapsulating mRNA for use in vitro and in vivo.

6,6′-Trehalose dioleate (6,6′-TDO) is a glycolipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.

YHS-12 is an ionizable cationic lipid (pKa = 6.506) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.

4-O10b1 is an ionizable cationic lipid (pKa = 5.148) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro and in vivo.

Alsactide is a peptide derivative of adrenocorticotropic hormone (ACTH), a peptide hormone found in the brain that is involved in the biological stress response.