GLPBio

Phospholipase

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Products Related to Phospholipase(136)

  • GC43670 structure
    GC43670FKGK 11
    CAS: 1071000-98-0
    Purity: >98.00%

    Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, yielding a free fatty acid and a lysophospholipid as products.

  • GC43671 structure
    GC43671FKGK 18
    CAS: 1071001-09-6
    Purity: >95.00%

    FKGK 18 is an inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2).

  • GC43695 structure
    GC43695Folipastatin
    CAS: 139959-71-0
    Purity: >95.00%

    Folipastatin is a fungal metabolite produced by A.

  • GC43701 structure
    GC43701FTY720 phenoxy-biotin
    Purity: >95.00%

    FTY720 is an immune modulator that down-regulates sphingosine-1-phosphate (S1P) receptors, enhances the activity of the sphingosine transporter ABCB1 and the leukotriene C4 transporter ABCC1 and inhibits cytosolic phospholipase A2 activity.

  • GC43756 structure
    GC43756GK187
    CAS: 1071001-50-7
    Purity: >95.00%

    GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism.

  • GC43812 structure
    GC43812HEPC
    CAS: 60793-01-3
    Purity: >95.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase activity.

  • GC43815 structure
    GC43815Heptanoyl thio-PC
    Purity: >98.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.

  • GC44222 structure
    GC44222ML-298
    CAS: 1426916-02-0
    Purity: >98.00%

    ML-298 is an inhibitor of phospholipase D2 (PLD2; IC50 = 355 nM).

  • GC44223 structure
    GC44223ML-299
    CAS: 1426916-00-8
    Purity: >95.00%

    ML-299 is a dual inhibitor of the two mammalian forms of phospholipase D (PLD), PLD1 and PLD2 (IC50s = 6 and 20 nM, respectively).

  • GC44549 structure
    GC44549Palmitoyl thio-PC
    CAS: 113881-60-0
    Purity: >98.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.

  • GC44661 structure
    GC44661PLC thio-PIP2 (sodium salt)
    Purity: >98.00%

    Phospholipase C (PLC) catalyzes the hydrolysis of phosphatidylinositol (4,5) bisphosphate (PIP2) on the cytoplasmic side of the cell membrane to yield diacylglycerol and inositol-1,4,5-triphosphate (IP3).

  • GC44664 structure
    GC44664p-Nitrophenylphosphorylcholine
    CAS: 21064-69-7
    Purity: >99.50%

    p-Nitrophenylphosphorylcholine is a synthetic chromogenic substrate commonly used in colorimetric detection of phospholipase C and related phosphodiesterase activities.

  • GC44764 structure
    GC44764PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt)
    Purity: >98.00%

    The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids.

  • GC44794 structure
    GC44794Pyrrophenone
    CAS: 341973-06-6
    Purity: >99.50%

    The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs).

  • GC44943 structure
    GC44943sPLA2 Inhibitor
    CAS: 393569-31-8
    Purity: >95.00%

    sPLA2 Inhibitor, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa).

  • GC45618 structure
    GC45618(±)-trans-GK563
    CAS: 2351820-19-2
    Purity: >94.00%

    A GVIA iPLA 2 inhibitor

  • GC45995 structure
    GC45995DO264
    CAS: 2301866-59-9
    Purity: >98.50%

    An ABHD12 inhibitor

  • GC46342 structure
    GC46342(R)-Bromoenol lactone-d7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46350 structure
    GC46350(S)-Bromoenol lactone-d7
    CAS: 478288-94-7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46352 structure
    GC46352(S)-DO271
    CAS: 2301865-01-8
    Purity: >98.00%

    An inactive control for DO264

  • GC46494 structure
    GC464941-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-PC
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46761 structure
    GC467619-Oxononanoic Acid
    CAS: 2553-17-5
    Purity: >98.00%

    An oxidized fatty acid

  • GC46955 structure
    GC46955Bromoenol lactone-d7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC47049 structure
    GC47049CAY10641
    CAS: 1233706-89-2
    Purity: >98.00%

    An inactive alcohol derivative of a highly potent cPLA 2 inhibitor