Phospholipase
Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.
Products Related to Phospholipase(136)
- GC49546Melittin (trifluoroacetate salt)Purity: >95.00%
The principal cytotoxic component of bee venom
- GC61040Melittin TFAPurity: >99.50%
Melittin TFA is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.
- GC61155Omeprazole sodiumCAS: 95510-70-6Purity: >98.00%
Omeprazole sodium (H 16868 sodium), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders.
- GC61344trans-BenzylideneacetoneCAS: 1896-62-4Purity: >99.00%
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2).
- GC61355Tris(2,4-di-tert-butylphenyl)phosphateCAS: 95906-11-9Purity: >98.00%
Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L.
- GC61689AlminoprofenCAS: 39718-89-3Purity: >99.00%
Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class.
- GC655953-NitrocoumarinCAS: 28448-04-6Purity: >97.00%
3-Nitrocoumarin is an effective and selective phospholipase C-γ (PLC-γ) inhibitor.
- GC67211BAPTA tetrapotassiumCAS: 73630-08-7Purity: >98%
BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49457 | Oleoyl-Coenzyme A (sodium salt) | - | >70.00% | |
An acyl-CoA thioester | ||||
| GC49546 | Melittin (trifluoroacetate salt) | - | >95.00% | |
The principal cytotoxic component of bee venom | ||||
| GC49635 | LY433771 | 220862-64-6 | >98.00% | |
An inhibitor of type X sPLA 2 | ||||
| GC49784 | AZD 2716 | 1845753-81-2 | >98.00% | |
An sPLA 2 inhibitor | ||||
| GC50726 | ASB 14780 | 1069046-00-9 | >98.00% | |
ASB 14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM. | ||||
| GC50738 | SGC 3027N | 2624313-14-8 | >98.00% | |
| GC52080 | LEI-110 | 2313525-90-3 | >98.00% | |
An AdPLA 2 inhibitor | ||||
| GC52197 | RSC-3388 | 337307-06-9 | >95.00% | |
| GC52315 | GK241 | 1899930-93-8 | >98.00% | |
An sPLA 2 (Type IIA) inhibitor | ||||
| GC60982 | LEI-401 | 2393840-15-6 | >99.50% | |
An NAPE-PLD inhibitor | ||||
| GC61040 | Melittin TFA | - | >99.50% | |
Melittin TFA is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2. | ||||
| GC61155 | Omeprazole sodium | 95510-70-6 | >98.00% | |
Omeprazole sodium (H 16868 sodium), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. | ||||
| GC61344 | trans-Benzylideneacetone | 1896-62-4 | >99.00% | |
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). | ||||
| GC61355 | Tris(2,4-di-tert-butylphenyl)phosphate | 95906-11-9 | >98.00% | |
Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. | ||||
| GC61689 | Alminoprofen | 39718-89-3 | >99.00% | |
Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. | ||||
| GC63860 | Rapanone | 573-40-0 | >99.00% | |
Rapanone naturally occurring hydroxyl-benzoquinone with a privileged chelating structure, having a broad spectrum of biological actions, highlighting its anti-inflammatory, anthelmintic, and cytotoxic activities. | ||||
| GC64070 | Omeprazole-d3-1 | 934293-92-2 | >98% | |
| GC64306 | ROC-0929 | 1048660-43-0 | >98% | |
ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s) with an IC50 of 80 nM, specially targeting hGX. | ||||
| GC64388 | CCT129957 | 883098-58-6 | >98.00% | |
CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. CCT129957 inhibits Ca2+ release in squamous carcinoma cells at ~15 μM. | ||||
| GC64957 | Ly93 | 1883528-69-5 | >98.00% | |
Ly93 is a selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC 50 of 91nM. | ||||
| GC65364 | SMS2-IN-1 | 2098890-15-2 | >98.00% | |
SMS2-IN-1 is a potent and highly selective inhibitor of sphingomyelin synthase 2 (SMS2), with an IC 50 value of 6.5nM for SMS2 and 1000nM for SMS1. | ||||
| GC65595 | 3-Nitrocoumarin | 28448-04-6 | >97.00% | |
3-Nitrocoumarin is an effective and selective phospholipase C-γ (PLC-γ) inhibitor. | ||||
| GC67211 | BAPTA tetrapotassium | 73630-08-7 | >98% | |
BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. | ||||
| GC67909 | GSK2647544 | 1380426-95-8 | >98% | |