GLPBio

Phospholipase

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Products Related to Phospholipase(136)

  • GC30610 structure
    GC30610LY 178002
    CAS: 107889-32-7
    Purity: >98%

    LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase.

  • GC31355 structure
    GC31355AA26-9
    CAS: 1312782-34-5
    Purity: >98.00%

    AA26-9 is a potent and broad spectrum serine hydrolase inhibitor.

  • GC31825 structure
    GC31825Varespladib methyl (A-002)
    CAS: 172733-08-3
    Purity: >99.50%

    Varespladib methyl (A-002) is a potent, broad-spectrum inhibitor of snake venom phospholipase A2 (PLA2).

  • GC32224 structure
    GC32224Lp-PLA2 -IN-1
    CAS: 1420367-28-7
    Purity: >99.00%

    Lp-PLA2 -IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor.

  • GC32768 structure
    GC32768Quinacrine dihydrochloride (Mepacrine dihydrochloride)
    CAS: 69-05-6
    Purity: >98%
  • GC33457 structure
    GC334571-Naphthaleneacetic acid (1-Naphthylacetic acid)
    CAS: 86-87-3
    Purity: >99.50%

    1-Naphthaleneacetic acid (1-Naphthylacetic acid) (1-Naphthylacetic acid), a synthetic auxin, can promote plant growth.

  • GC35065 structure
    GC350651-Linoleoyl Glycerol
    CAS: 2277-28-3
    Purity: >98.00%

    1-Linoleoyl Glycerol is a fatty acid glycerol.

  • GC35390 structure
    GC35390Aristolochic acid C
    CAS: 4849-90-5
    Purity: >99.50%

    An alkaloid with anticancer activity

  • GC37674 structure
    GC37674SPK-601
    CAS: 1096687-52-3
    Purity: >98.00%

    SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC).

  • GC40545 structure
    GC40545cis-Parinaric Acid
    CAS: 18427-44-6
    Purity: >90.00%

    cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene.

  • GC40678 structure
    GC40678(R)-Bromoenol lactone
    CAS: 478288-90-3
    Purity: >98.00%

    The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components.

  • GC40679 structure
    GC40679(S)-Bromoenol lactone
    CAS: 478288-94-7
    Purity: >98.00%

    The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components.

  • GC40794 structure
    GC40794Sphinganine (d18:0)
    CAS: 764-22-7
    Purity: >98.00%

    Sphinganine (d18:0) is an intermediate in the sphingolipid metabolic pathway.

  • GC41004 structure
    GC41004Rhamnetin
    CAS: 90-19-7
    Purity: >99.50%

    Rhamnetin is a natural flavonoid that has been isolated from a variety of plants.

  • GC41782 structure
    GC417821,2-bis(heptanoylthio) Glycerophosphocholine
    CAS: 89019-63-6
    Purity: >95.00%

    Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).

  • GC41808 structure
    GC418081,2-Dioctanoyl PC
    CAS: 19191-91-4
    Purity: >99.00%

    Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane.

  • GC42029 structure
    GC420291-Palmitoyl-2-linoleoyl PE
    CAS: 26662-95-3
    Purity: >98.00%

    Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis.

  • GC42611 structure
    GC426117-hydroxycoumarinyl-γ-Linolenate
    CAS: 161180-12-7

    7-hydroxycoumarinyl-γ-Linolenate is a γ-linolenic acid ester of 7-hydroxycoumarin (umbelliferone) that behaves as a substrate for cPLA2.

  • GC42843 structure
    GC42843Arachidonoyl thio-PC
    CAS: 146797-82-2
    Purity: >98.00%

    Arachidonoyl Thio-PC is a substrate for many phospholipase A2s (PLA2s) including sPLA2, cPLA2, and iPLA2.

  • GC42855 structure
    GC42855ARN19874
    CAS: 2190502-57-7
    Purity: >98.00%

    ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD; IC50 = 33.7 μM).

  • GC42885 structure
    GC42885AX 048
    CAS: 873079-69-7
    Purity: >98.00%

    The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes.

  • GC43161 structure
    GC43161CAY10502
    CAS: 888320-29-4
    Purity: >95.00%

    Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids.

  • GC43179 structure
    GC43179CAY10590
    CAS: 1101136-50-8
    Purity: >98.00%

    Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, liberating arachidonic acid for subsequent eicosanoid synthesis.

  • GC43305 structure
    GC43305Compound 48/80 (hydrochloride)
    CAS: 848035-21-2
    Purity: >98.00%

    Compound 48/80 trihydrochloride is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde.