GLPBio

Ligand for E3 Ligase

The PROTAC molecule consists of a ligand, which binds an E3 ubiquitin ligase, connected by a linker to another ligand that binds the target protein.

The association between a protein and an E3 ligase, as induced by a PROTAC molecule, will lead to the transfer of ubiquitin and degradation of the targeted protein.

Products Related to Ligand for E3 Ligase(166)

  • GC80950 structure
    GC80950CRBN ligand-881
    CAS: 92137-90-1
    Purity: >99.00%

    CRBN ligand-881 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80951 structure
    GC80951Hydrouracil-3-PhOH
    CAS: 1310680-01-3
    Purity: >98.00%

    Hydrouracil-3-PhOH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80952 structure
    GC80952CRBN ligand-885
    CAS: 2758531-21-2
    Purity: >98.00%

    CRBN ligand-885 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80953 structure
    GC80953CRBN ligand-225
    CAS: 83809-75-0
    Purity: >98.00%

    CRBN ligand-225 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80954 structure
    GC80954CRBN ligand-883
    CAS: 1502483-16-0
    Purity: >99.50%

    CRBN ligand-883 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80955 structure
    GC80955Hydrouracil-3-Ph-COOH
    CAS: 2377644-59-0
    Purity: >98.50%

    Hydrouracil-3-Ph-COOH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80956 structure
    GC80956CRBN ligand-224
    CAS: 2599846-40-7
    Purity: >98.50%

    CRBN ligand-224 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80957 structure
    GC80957CRBN ligand-891
    CAS: 2618349-23-6
    Purity: >95.00%

    CRBN ligand-891 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80958 structure
    GC80958Hydrouracil-4-fluorobenzoate
    CAS: 2377643-38-2
    Purity: >98.00%

    Hydrouracil-4-fluorobenzoate is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80959 structure
    GC80959E3 ligase Ligand 79
    CAS: 2152672-96-1
    Purity: >98.00%

    E3 ligase Ligand 79 is a CRBN E3 ligase ligand that can be used for synthesis of PROTACs [1] .

  • GC80960 structure
    GC80960Desamino lenalidomide-6-OH
    CAS: 1416990-09-4
    Purity: >99.00%

    Desamino lenalidomide-6-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80961 structure
    GC80961Desamino lenalidomide-7-OH
    CAS: 1416990-10-7
    Purity: >99.00%

    Desamino lenalidomide-7-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80962 structure
    GC80962Desamino lenalidomide-5-F
    CAS: 2468780-76-7
    Purity: >97.50%

    Desamino lenalidomide-5-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80963 structure
    GC80963Desamino lenalidomide-7-F
    CAS: 2287267-33-6
    Purity: >98.00%

    Desamino lenalidomide-7-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80964 structure
    GC80964CRBN ligand-888
    CAS: 53727-25-6
    Purity: >99.00%

    CRBN ligand-888 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80965 structure
    GC80965Desamino lenalidomide-ethynyl
    CAS: 1416990-26-5
    Purity: >98%

    Desamino lenalidomide-ethynyl is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80966 structure
    GC80966Desamino lenalidomide-6-propyne
    CAS: 2412439-22-4
    Purity: >97.50%

    Desamino lenalidomide-6-propyne is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80967 structure
    GC809674-Chloro-3-(2,4-dioxo-1,3-diazinan-1-yl)benzoic acid
    CAS: 2377645-90-2
    Purity: >98.00%

    4-Chloro-3-(2,4-dioxo-1,3-diazinan-1-yl)benzoic acid is an E3 ligase ligand that can be used in the recruitment of CRBN protein.

  • GC80968 structure
    GC80968Desamino lenalidomide-cyano
    CAS: 2639386-82-4
    Purity: >99.50%

    Desamino lenalidomide-cyano is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80969 structure
    GC80969Desamino lenalidomide-5-acetonitrile
    CAS: 1010100-27-2
    Purity: >99.50%

    Desamino lenalidomide-5-acetonitrile is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80970 structure
    GC80970Desamino lenalidomide-4-acetonitrile
    CAS: 444289-04-7
    Purity: >95.50%

    Desamino lenalidomide-4-acetonitrile is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80971 structure
    GC80971N-Methylthalidomide
    CAS: 42472-93-5
    Purity: >98.00%

    N-Methylthalidomide is a cereblon ligand derivative that acts as an E3 ubiquitin ligase ligand for the synthesis of PROTAC LLC0424 N.

  • GC80972 structure
    GC80972Glutarimide-(1-oxoisoindoline-5-carbaldehyde)
    CAS: 2582979-82-4
    Purity: >97.00%

    Glutarimide-(1-oxoisoindoline-5-carbaldehyde) is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.

  • GC80973 structure
    GC80973Desamino lenalidomide-5-CO
    CAS: 2866307-09-5
    Purity: >98.00%

    Desamino lenalidomide-5-CO is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.