PY109 is an orally active and highly selective aryl hydrocarbon receptor ( AHR ) agonist. PY109's EC 50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis [1].
PY109
Catalog No.: GC79393Purity:>99.00%
PY109 is an orally active and highly selective aryl hydrocarbon receptor ( AHR ) agonist.
Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.
Cas No.: 2378039-23-5
10mM (in 1mL DMSO)In Stock
$32.00
1
5mgIn Stock
$29.00
1
10mgIn Stock
$45.00
1
25mgIn Stock
$79.00
1
50mgIn Stock
$123.00
1
100mgIn Stock
$194.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $32.00 | In Stock | 1 | |
| 5mg | $29.00 | In Stock | 1 | |
| 10mg | $45.00 | In Stock | 1 | |
| 25mg | $79.00 | In Stock | 1 | |
| 50mg | $123.00 | In Stock | 1 | |
| 100mg | $194.00 | In Stock | 1 |
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Citas (Citations)
Actualmente no hay citas disponibles para este producto. A continuación se muestran publicaciones seleccionadas que citan productos GlpBio.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Descripción (Description)
Documentos del producto (Product Documents)
Purity:>99.00%Appearance:A solid
Propiedades químicas (Chemical Properties)
N.º CAS
2378039-23-5
Fórmula molecular
C15H9F3N2O
Peso molecular
290.24
Solubilidad
DMSO: 100 mg/mL (344.54 mM; Need ultrasonic)
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.
Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad
g/mol
Reviews
Review for PY109
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