GLPBio

Androgen Receptor

AR (androgen receptor) is a member of steroid hormone receptor and ligand-activated transcription factor. It plays a crucial role in prostate cellular proliferation and male sexual differentiation.

Products Related to Androgen Receptor(159)

  • GC16649 structure
    GC16649TAK-700 (Orteronel)
    CAS: 426219-18-3
    Purity: >98%

    A non-steroidal inhibitor of the 17,20-lyase activity of CYP17A1

  • GC16840 structure
    GC16840ARN-509
    CAS: 956104-40-8
    Purity: >99.50%

    ARN-509 is a synthetic biaryl thiohydantoin compound that inhibits androgen receptor (AR), with an IC 50 value of 16nM.

  • GC17160 structure
    GC171602-hydroxy Flutamide
    CAS: 52806-53-8
    Purity: >98%

    2-hydroxy Flutamide (HF), an active metabolite of Flutamide, is a potent androgen receptor antagonist (IC50=700 nM). 2-hydroxy Flutamide can be used for the research of prostate cancer.

  • GC17491 structure
    GC17491CITCO
    CAS: 338404-52-7
    Purity: >99.50%

    Constitutive androstane receptor (CAR) agonist

  • GC17557 structure
    GC1755717 alpha-propionate
    CAS: 19608-29-8
    Purity: >98.50%

    A peripherally selective androgen receptor antagonist

  • GC17679 structure
    GC17679GSK2881078
    CAS: 1539314-06-1
    Purity: >99.00%

    selective androgen receptor modulator (SARM)

  • GC18496 structure
    GC18496Leelamine (hydrochloride)
    CAS: 16496-99-4
    Purity: >98%

    Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means 'play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM.

  • GC19305 structure
    GC19305RAD140
    CAS: 1182367-47-0
    Purity: >99.00%

    RAD140 (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a Ki of 7 nM.

  • GC19458 structure
    GC194586β-hydroxy Testosterone
    CAS: 62-99-7
    Purity: >97.00%

    CYP3A4 and CYP3A5 are cytochrome P450 enzymes whose expression is induced by glucocorticoids and certain xenobiotics, including many drugs and chemical carcinogens.

  • GC19800 structure
    GC19800Metribolone
    CAS: 965-93-5
    Purity: >98.00%

    Metribolone (R1881), also known as methyltrienolone, is a synthetic androgen ligand that binds strongly to the androgen receptor (AR) with a K i value of 0.09nM.

  • GC26431 structure
    GC26431Pentacosafluorotridecanoic Acid
    CAS: 72629-94-8
    Purity: >97.00%

    Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant

  • GC30086 structure
    GC30086GLPG0492
    CAS: 1215085-92-9
    Purity: >99.50%

    A selective androgen receptor modulator

  • GC30101 structure
    GC30101GLPG0492 R enantiomer
    CAS: 1215085-93-0
    Purity: >99.50%

    GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator.

  • GC30710 structure
    GC30710(R)-UT-155
    CAS: 2031161-54-1
    Purity: >98.00%

    (R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer.

  • GC31254 structure
    GC31254Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- (Androst-4-ene-3β,17β-diol, dipropionate)
    CAS: 56699-31-1
    Purity: >98%
  • GC31380 structure
    GC31380LY2452473
    CAS: 1029692-15-6
    Purity: >98.00%

    LY2452473 is a selective androgen receptor modulator (SARM).

  • GC31441 structure
    GC31441DJ-V-159
    CAS: 2253744-53-3
    Purity: >99.50%

    DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).

  • GC31442 structure
    GC31442YK11
    CAS: 1370003-76-1
    Purity: >98.00%

    A partial agonist of the androgen receptor

  • GC31577 structure
    GC31577Bifluranol (BX341)
    CAS: 34633-34-6
    Purity: >98.50%

    Bifluranol (BX341) (BX341) is an anti-androgen.

  • GC31738 structure
    GC31738ACP-105
    CAS: 899821-23-9
    Purity: >99.00%

    ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively.

  • GC31742 structure
    GC31742Ailanthone (δ13-Dehydrochaparrinone)
    CAS: 981-15-7
    Purity: >98.00%

    Ailanthone (δ13-Dehydrochaparrinone), a quassinoid extract from the traditional Chinese medicine plant Ailanthus altissima , is a potent inhibitor of both full-length androgen receptor (AR) (IC 50 =69nM) and constitutively active truncated AR splice variants (AR-Vs IC 50 =309nM).

  • GC32402 structure
    GC32402ORM-15341
    CAS: 1297537-33-7
    Purity: >98.50%

    ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct.

  • GC32403 structure
    GC32403LGD-3303
    CAS: 917891-35-1
    Purity: >98.00%

    LGD-3303 is an orally active, non-steroidal selective androgen receptor modulator (SARM) with high affinity for the androgen receptor (K i =0.9nM).

  • GC32408 structure
    GC32408LGD-4033 (Ligandrol)
    CAS: 1165910-22-4
    Purity: >98%

    LGD-4033 (Ligandrol), belongs to the group of selective androgen receptor modulators (SARMs).