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PD-1/PD-L1 inhibitor 2 (Synonyms: BMS202)

Katalog-Nr.GC16762

PD-1/PD-L1-Inhibitor 2 ist ein potenter und nicht-peptidischer PD-1/PD-L1-Komplex-Inhibitor mit einem IC50 von 18 nM und einer KD von 8 μM. PD-1/PD-L1-Inhibitor 2 bindet an PD-L1 und blockiert die Interaktion mit menschlichem PD-1/PD-L1. PD-1/PD-L1-Inhibitor 2 hat AntitumoraktivitÄt.

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PD-1/PD-L1 inhibitor 2 Chemische Struktur

Cas No.: 1675203-84-5

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25mg
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

BMS-202 is a potent PD-1/PD-L1 inhibitor, which binds to PD-1 and inhibits human PD-1/PD-L1 interaction, with an IC50 of 18 nM[1].

References:
[1]. Zak KM, et al. Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget. 2016 May 24;7(21):30323-35.

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