GNE-4997 |
| Katalog-Nr.GC32053 |
GNE-4997 ist ein potenter und selektiver Inhibitor der Interleukin-2-induzierbaren T-Zell-Kinase (ITK) mit einem Ki von 0,09 nM, und die Korrelation zwischen der BasizitÄt der solubilisierenden Elemente in GNE-4997 und antiproliferativen Wirkungen außerhalb des Ziels verringert die ZytotoxizitÄt[ 1].
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1705602-02-3
Sample solution is provided at 25 µL, 10mM.
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GNE-4997 is a potent and selective ITK/TSK inhibitor.
[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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