CV-6209 (chloride) |
| Katalog-Nr.GC43333 |
CV-6209 (Chlorid) ist ein potenter Antagonist des Thrombozytenaktivierungsfaktors (PAF).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 100488-87-7
Sample solution is provided at 25 µL, 10mM.
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CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid , histamine, bradykinin , or isoproterenol . CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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