FGFR
FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.
Products Related to FGFR(109)
- GC73852Infigratinib-BocCAS: 2504949-83-9Purity: >98.00%
Infigratinib-Boc ist ein Derivat von Infigratinib, das eine Boc (t-Butyloxycarbonyl)-Gruppe enthält.
- GC74365VSPPLTLGQLLSCAS: 1206896-24-3Purity: >98.00%
VSPPLTLGQLLS ist ein kleiner Peptid FGFR3-Inhibitor, Peptid P3, hemmt die FGFR3-Phosphorylierung.
- GC813192,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucroseCAS: 150302-84-4Purity: >98%
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica.
- GC81325VEGFR2-IN-84CAS: 861877-12-5Purity: >98%
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold.
- GC81329TCB-32 hydrochlorideCAS: 169764-95-8Purity: >97.50%
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.
- GN10527FormononetinCAS: 485-72-3Purity: >99.50%
Formononetin is a potent FGFR2 inhibitor with an IC 50 of 4.3μM. Formononetin potently inhibits angiogenesis and tumor growth.
- GN10540Fumalic acidCAS: 1135-24-6Purity: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73852 | Infigratinib-Boc | 2504949-83-9 | >98.00% | |
Infigratinib-Boc ist ein Derivat von Infigratinib, das eine Boc (t-Butyloxycarbonyl)-Gruppe enthält. | ||||
| GC73947 | CEP-11981 | 856691-93-5 | >99.00% | |
CEP-11981(ESK981; BOL 303213X) ist ein oral aktiver Tyrosinkinase-Inhibitor (TKI), der TIE2, VEGFR1-3 und FGFR1 angreifen kann und potentielle Anti-Tumor- und Anti-Angiogene-Effekte hat. | ||||
| GC74046 | BR-cpd7 | - | >98.00% | |
BR-cpd7 ist ein PROTAC-Abbau für Fibroblasten-Wachstumsfaktor-Rezeptor FGFR1/2 mit DC50 von 10 nM. | ||||
| GC74365 | VSPPLTLGQLLS | 1206896-24-3 | >98.00% | |
VSPPLTLGQLLS ist ein kleiner Peptid FGFR3-Inhibitor, Peptid P3, hemmt die FGFR3-Phosphorylierung. | ||||
| GC79483 | MD-3-A45 | 2314337-87-4 | >98.00% | |
MD-3-A45 is an inhibitor of fibroblast growth factor 23 ( FGF-23 ). | ||||
| GC81314 | OM-RCA-01 | - | >99.00% | |
OM-RCA-01 is an anti- FGFR1 monoclonal antibody with a K d of 1.59 nM for human FGFR1. | ||||
| GC81319 | 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose | 150302-84-4 | >98% | |
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81325 | VEGFR2-IN-84 | 861877-12-5 | >98% | |
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold. | ||||
| GC81329 | TCB-32 hydrochloride | 169764-95-8 | >97.50% | |
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM. | ||||
| GC91419 | CYY292 | 2644673-04-9 | >98.00% | |
CYY292 ist ein Inhibitor von PDGFRα, PDGFRβ, FGFR1,-2 und -3 (IC50s = 5,35, 4,6, 28, 28 bzw. 78 nM). | ||||
| GN10527 | Formononetin | 485-72-3 | >99.50% | |
Formononetin is a potent FGFR2 inhibitor with an IC 50 of 4.3μM. Formononetin potently inhibits angiogenesis and tumor growth. | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||