Disopyramide is a sodium channel blocker that, in rabbit ventricular myocytes, binds and dissociates from open channels more quickly than from resting channels. It is a class Ia antiarrhythmic agent that delays conduction through the AV node and ventricles of the dog heart both in vivo (3 and 5 mg/kg) and in vitro (1-2 mg/L). Formulations containing disopyramide have been used in the treatment of cardiac arrhythmias and hypertrophic cardiomyopathy.
Disopyramide
Catalog No.: GC43478Purity:>98.00%Synonyms: (±)-Disopyramide, Ritmilen, SC-7031
Disopyramide is a sodium channel blocker that, in rabbit ventricular myocytes, binds and dissociates from open channels more quickly than from resting channels.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3737-09-5
10mM (in 1mL DMSO)In Stock
$19.00
1
5mgIn Stock
$17.00
1
10mgIn Stock
$25.00
1
25mgIn Stock
$36.00
1
50mgIn Stock
$49.00
1
100mgIn Stock
$69.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $19.00 | In Stock | 1 | |
| 5mg | $17.00 | In Stock | 1 | |
| 10mg | $25.00 | In Stock | 1 | |
| 25mg | $36.00 | In Stock | 1 | |
| 50mg | $49.00 | In Stock | 1 | |
| 100mg | $69.00 | In Stock | 1 |
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com
Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
3737-09-5
Synonyms
(±)-Disopyramide, Ritmilen, SC-7031
SMILES
O=C(N)C(C1=CC=CC=C1)(CCN(C(C)C)C(C)C)C2=CC=CC=N2
Molecular Formula
C21H29N3O
Molecular Weight
339.5
Solubility
Chloroform: slightly soluble,Ethanol: >1 mg/ml,Methanol: slightly soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
Review for Disopyramide
Rating: 5
- 5 Star100%
- 4 Star0%
- 3 Star0%
- 2 Star0%
- 1 Star0%