DNA Alkylating
DNA alkylating is the transfer of alkyl groups to particular bases, resulting in alkylation products such as O2‐alkylthymine and O6‐methylguanine that lead to DNA mutations.
Products Related to DNA Alkylating(23)
- GC13667TemozolomideCAS: 85622-93-1Purity: >98.50%
Temozolomide is an oral activity alkylating agent that induces the formation of O6-methylguanine in DNA, which mispairs with thymine during the following cycle of DNA replication, leading to activation of the apoptotic pathways, Temozolomide could crosses the blood-brain barrier and is indicated for malignant gliomas and metastatic melanomas.
- GC15043TrioxsalenCAS: 3902-71-4Purity: >99.00%
intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks when activated with ultraviolet light
- GC44243Monohydroxy Melphalan (hydrochloride)CAS: 2707535-88-2Purity: >95.00%
Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan.
- GC44348N-desmethyl BendamustineCAS: 41515-13-3Purity: >95.00%
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine.
- GC46914Bendamustine-d4 (hydrochloride)CAS: 2802569-31-7Purity: >99.00%
A neuropeptide with diverse biological activities
- GC47078Chlorambucil-d8CAS: 2748247-26-7Purity: >99.00%
A neuropeptide with diverse biological activities
- GC47167Dacarbazine-d6CAS: 1185241-28-4Purity: >99.00%
An internal standard for the quantification of dacarbazine
- GC52076Temozolomide AcidCAS: 113942-30-6Purity: >98.00%
Temozolomide Acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide Acid has an activity similar to the parent compound Temozolomide with the same anticancer activity.
- GC91899Carmustine-d8Purity: >99.00%
Carmustine-d8 is intended for use as an internal standard for the quantification of carmustine by GC- or LC-MS.
- GC15793CarmustineCAS: 154-93-8Purity: >98.00%
cell-cycle phase nonspecific alkylating antineoplastic agent
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC13667 | Temozolomide | 85622-93-1 | >98.50% | |
Temozolomide is an oral activity alkylating agent that induces the formation of O6-methylguanine in DNA, which mispairs with thymine during the following cycle of DNA replication, leading to activation of the apoptotic pathways, Temozolomide could crosses the blood-brain barrier and is indicated for malignant gliomas and metastatic melanomas. | ||||
| GC13671 | Busulfan | 55-98-1 | >97.00% | |
Busulfan is an alkylating drug alkylates DNA, with an IC 50 value of 77μM for human serum Paraoxonase 1. | ||||
| GC14564 | Altretamine | 645-05-6 | >99.50% | |
Antineoplastic agent | ||||
| GC16158 | Thio-TEPA | 52-24-4 | >98.00% | |
alkylating agent used to treat cancer | ||||
| GC17865 | Lomustine | 13010-47-4 | >99.50% | |
Antineoplastic drug | ||||
| GC14762 | Palifosfamide | 31645-39-3 | >98% | |
An active metabolite of ifosfamide | ||||
| GC15043 | Trioxsalen | 3902-71-4 | >99.00% | |
intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks when activated with ultraviolet light | ||||
| GC18100 | Illudin S | 1149-99-1 | >98.50% | |
potent antitumor sesquiterpene | ||||
| GC41384 | K-TMZ | 2269482-26-8 | >95.00% | |
K-TMZ is a DNA alkylating agent. | ||||
| GC44243 | Monohydroxy Melphalan (hydrochloride) | 2707535-88-2 | >95.00% | |
Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan. | ||||
| GC44251 | MTIC | 3413-72-7 | >99.50% | |
MTIC is a DNA alkylating agent, an active metabolite of dacarbazine, and an active degradation product of temozolomide. | ||||
| GC44348 | N-desmethyl Bendamustine | 41515-13-3 | >95.00% | |
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine. | ||||
| GC46914 | Bendamustine-d4 (hydrochloride) | 2802569-31-7 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47078 | Chlorambucil-d8 | 2748247-26-7 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47167 | Dacarbazine-d6 | 1185241-28-4 | >99.00% | |
An internal standard for the quantification of dacarbazine | ||||
| GC49470 | 1-Ethyl-1-nitrosourea (hydrate) | - | >95.00% | |
A DNA alkylating agent | ||||
| GC52076 | Temozolomide Acid | 113942-30-6 | >98.00% | |
Temozolomide Acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide Acid has an activity similar to the parent compound Temozolomide with the same anticancer activity. | ||||
| GC52129 | 3-Amino-5-hydroxybenzoic Acid | 76045-71-1 | >98.00% | |
| GC90549 | 5-Aminoimidazole-4-carboxamide (hydrate) | - | >95.00% | |
A synthetic precursor | ||||
| GC90657 | COMC | 106281-45-2 | >90.00% | |
An anticancer agent | ||||
| GC91297 | Cholesterol-Doxorubicin | - | >95.00% | |
A prodrug form of doxorubicin | ||||
| GC91899 | Carmustine-d8 | - | >99.00% | |
Carmustine-d8 is intended for use as an internal standard for the quantification of carmustine by GC- or LC-MS. | ||||
| GC15793 | Carmustine | 154-93-8 | >98.00% | |
cell-cycle phase nonspecific alkylating antineoplastic agent | ||||