Norleual |
| Catalog No.GC50152 |
Highly potent HGF/c-MET inhibitor; also AT4 antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 334994-34-2
Sample solution is provided at 25 µL, 10mM.
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Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic.
Yamamoto et al (2010) The angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor. J.Pharmacol.Exp.Ther. 333 161 PMID:20086056
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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