Psammaplin A |
| Catalog No.GC60310 |
La psammapline A, un métabolite marin, est un puissant inhibiteur des HDAC et des ADN méthyltransférases.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 110659-91-1
Sample solution is provided at 25 µL, 10mM.
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Psammaplin A, a marine metabolite, is a potent inhibitor of HDAC and DNA methyltransferases. Psammaplin A ia a highly potent and selective DAC1 inhibitor with an IC50 of 0.9 nM. Psammaplin A possess the antimicrobial effect on the Gram-positive bacteria and inhibits DNA synthesis and DNA gyrase activity. Antitumor Activity[1][2].
[1]. Matthias G J Baud, et al. Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A Against Its Epigenetic Targets. J Med Chem. 2012 Feb 23;55(4):1731-50. [2]. Psammaplin A, a Natural Bromotyrosine Derivative From a Sponge, Possesses the
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