GLPBio

Prednisolone farnesylate

Catalog No.: GC36959Purity:>98%
COASDSData Sheet
Prednisolone farnesylate (PNF21) is a new transdermal corticosteroid with anti-inflammatory activity.

Products are for research use only. Not for human use. We do not sell to patients.

Prednisolone farnesylate
Cas No.: 118244-44-3
1mgIn Stock
$371.00
1
5mgIn Stock
$742.00
1
10mgIn Stock
$1,261.00
1
20mgIn Stock
$2,225.00
1
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Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Prednisolone farnesylate (PNF21) is a new transdermal corticosteroid with anti-inflammatory activity.

Prednisolone farnesylate is a synthetic glucocorticoid, which is a compound of Prednisolone and its ester Farnesylate and is known to suppress local swelling of the adjuvant-induced arthritis[1].

[1]. Kato N, et al. Treatment of the chronic inflammation in peripheral target tissue improves the crushed nerve recovery in the rat: histopathological assessment of the nerve recovery. J Neurol Sci. 2002 Oct 15;202(1-2):69-74.

Chemical Properties

CAS No.
118244-44-3
SMILES
C[C@@]12[C@](CC[C@]2(O)C(COC(/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=O)=O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([H])[C@@H](O)C1
Molecular Formula
C36H50O6
Molecular Weight
578.78
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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