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Somatostatin-28 (trifluoroacetate salt)

Catalog No.GC44916

Somatostatin-28 (trifluoroacetate salt) Chemical Structure

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Sample solution is provided at 25 µL, 10mM.

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Somatostatin-28 is a cyclic neuropeptide hormone that has a role in endocrine regulation. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.60, 0.12, 0.22, 0.83, and 0.41 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 5.13, 1.91, 6.46, 2.95, and 3.55 nM, respectively). Somatostatin-28 stimulates growth hormone (GH) release from primary porcine pituitary cells when used at a concentration of 1 fM. It inhibits acid secretion induced by gastrin I and IBMX in isolated rat gastric mucosa (EC50s = 27 and 252 nM, respectively). In vivo, somatostatin-28 dose-dependently increases basal and pentagastrin-induced gastric acid secretion in rats.

Chemical Properties

Cas No. N/A SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES N/A
Formula C137H207N41O39S3•XCF3COOH M.Wt 3148.6
Solubility Formic Acid: 1 mg/ml Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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