mTOR
MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.
Products Related to mTOR(132)
- GC72768Desmethyl-VS-5584 hydrochloridePurity: >98.00%
Desmethyl-VS-5584 hydrochloride는 피리딘 [2,3-d] 피리 미딘 구조를 갖는 강력하고 선택적인 이중 mTOR/PI3K 억제제인 VS-5584의 디메틸 아날로그입니다.
- GC72931HTH-01-091 TFAPurity: >98.00%
HTH-01-091 TFA은 10.5 nM의 IC50으로 강력하고 선택적인 모체 배아성 루신 지퍼 키나아제 (MELK) 억제제이다.
- GC74029ASCT2-IN-1CAS: 3032651-18-3Purity: >98.00%
ASCT2-IN-1 (화합물 20k)은 IC50 값이 있는 ASCT2 억제의 5. 6 μ M과 3. 5 μ M 세포 A549 그리고 HEK293, 각각이다.
- GC79141T7 Peptide TFAPurity: >98.00%
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor.
- GC79231RMC-4998 TFAPurity: >99.00%
RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant.
- GC79326Tirzepatide sodiumPurity: >98.00%
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist.
- GC79339Anti-CD160 Antibody (MAT 302)Purity: >97.00%
Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160.
- GC79430Anti-IL11 Antibody (X203, Mouse IgG)Purity: >99.00%
Anti-IL11 Antibody (X203, Mouse IgG ) is an antibody targeting IL-11.
- GC79816CryptolepineCAS: 480-26-2Purity: >98%
Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties.
- GC80852Gedatolisib-d 8Purity: >98.50%
Gedatolisib -d 8 (PKI-587-d 8 ) is the deuterium labeled Gedatolisib.
- GC81042PI3K/mTOR ligand-1CAS: 1197160-66-9Purity: >97.00%
PI3K/mTOR ligand-1 is a ligand for the target protein of PROTAC ( PI3K / mTOR ).
- GC81682Sialorphin TFAPurity: >97.00%
Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC72768 | Desmethyl-VS-5584 hydrochloride | - | >98.00% | |
Desmethyl-VS-5584 hydrochloride는 피리딘 [2,3-d] 피리 미딘 구조를 갖는 강력하고 선택적인 이중 mTOR/PI3K 억제제인 VS-5584의 디메틸 아날로그입니다. | ||||
| GC72931 | HTH-01-091 TFA | - | >98.00% | |
HTH-01-091 TFA은 10.5 nM의 IC50으로 강력하고 선택적인 모체 배아성 루신 지퍼 키나아제 (MELK) 억제제이다. | ||||
| GC72950 | NEO214 | 1361198-80-2 | >98.00% | |
NEO214는 오토 파지 저해제 및 PDE4 저해제 Rolipram 및 perillyl 알코올의 공유 결합 결합체입니다. | ||||
| GC73642 | ALK-IN-26 | 2447607-85-2 | >99.00% | |
ALK-IN-26은 IC50와 함께 ALK 억제 ALK 값의 7. 0 μ M-dopa 산화효소다. | ||||
| GC73678 | RMC-4998 | 2642037-07-6 | >96.00% | |
RMC-4998은 KRASG12C 돌연변이의 활성 또는 gtp 결합 상태를 목표로 하는 구강 활성 억제제이다. | ||||
| GC73729 | IBL-302 | 1414455-21-2 | >98.00% | |
IBL-302 (AMU302)는 경구용 PIM과 PI3K/AKT/mTOR 이중 신호 억제제로서 유방암과 신경모세포종에 대한 활성을 가지고 있다. | ||||
| GC73974 | SKI-349 | 727686-80-8 | >99.50% | |
SKI-349 는 메탄올 효소 1/2 (SPHK1/2) 와 마이크로튜브 조립 (MDA) 의 이중 표적 억제제입니다. | ||||
| GC73992 | KTC1101 | 2764833-47-6 | >98.00% | |
KTC1101 는 경구 활성 pan-PI3K 억제제의 일종이다. | ||||
| GC74029 | ASCT2-IN-1 | 3032651-18-3 | >98.00% | |
ASCT2-IN-1 (화합물 20k)은 IC50 값이 있는 ASCT2 억제의 5. 6 μ M과 3. 5 μ M 세포 A549 그리고 HEK293, 각각이다. | ||||
| GC74030 | ASCT2-IN-2 | - | >99.00% | |
ASCT2-IN-2 (화합물 25e) 는 ASCT2 억제제로서 IC50은 5.14 μM입니다. | ||||
| GC74689 | WRX606 | 899937-47-4 | >95.00% | |
WRX606은 mTOR complex 1 (mTORC1)의 억제제이다. | ||||
| GC78981 | HBS-101 | - | >99.50% | |
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor ( K D = 38.4 nM). | ||||
| GC79141 | T7 Peptide TFA | - | >98.00% | |
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor. | ||||
| GC79231 | RMC-4998 TFA | - | >99.00% | |
RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant. | ||||
| GC79326 | Tirzepatide sodium | - | >98.00% | |
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist. | ||||
| GC79339 | Anti-CD160 Antibody (MAT 302) | - | >97.00% | |
Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160. | ||||
| GC79430 | Anti-IL11 Antibody (X203, Mouse IgG) | - | >99.00% | |
Anti-IL11 Antibody (X203, Mouse IgG ) is an antibody targeting IL-11. | ||||
| GC79816 | Cryptolepine | 480-26-2 | >98% | |
Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties. | ||||
| GC80852 | Gedatolisib-d 8 | - | >98.50% | |
Gedatolisib -d 8 (PKI-587-d 8 ) is the deuterium labeled Gedatolisib. | ||||
| GC80869 | Calebin A | 336784-82-8 | >98.00% | |
Calebin A is a PI3K/Akt/mTOR, MAPK, and NF-κB inhibitor with oral effectiveness. | ||||
| GC81041 | GP262 | 3107761-81-6 | >98.50% | |
GP262 is a PI3K/mTOR PROTAC degrader targeting PI3Kγ, PI3Kα and mTOR with DC 50 values of 42.23 nM, 227.4 nM and 45.4 nM, respectively in MDA-MB-231 cells. | ||||
| GC81042 | PI3K/mTOR ligand-1 | 1197160-66-9 | >97.00% | |
PI3K/mTOR ligand-1 is a ligand for the target protein of PROTAC ( PI3K / mTOR ). | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81682 | Sialorphin TFA | - | >97.00% | |
Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals. | ||||