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Stem Cell

Research Areas

Products Related to Stem Cell(471)

  • GC43809 structure
    GC43809Hedgehog Antagonist VIII
    CAS: 330796-24-2
    Purity: >98.00%

    Hedgehog (Hh) proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened.

  • GC43847 structure
    GC43847Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt)
    Purity: >95.00%

    Histone H3K27Me2 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences.

  • GC43848 structure
    GC43848Histone H3K27Me2 (23-34) (trifluoroacetate salt)
    Purity: >95.00%

    Histone H3K27Me2 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.

  • GC43873 structure
    GC43873Hydrocortisone 21-hemisuccinate (sodium salt)
    CAS: 125-04-2
    Purity: >98.00%

    Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol.

  • GC44080 structure
    GC44080LLP-3
    CAS: 1453835-43-2
    Purity: >95.00%

    LLP-3는 암세포에서 Survivin-Ran 상호 작용을 방해하는 강력한 Survivin 억제제입니다. LLP-3는 다형성 교모세포종(GBM) 연구에 사용할 수 있습니다.

  • GC44213 structure
    GC44213ML115
    CAS: 912798-42-6
    Purity: >98.00%

    Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer.

  • GC44245 structure
    GC44245MoTP
    CAS: 57055-82-0
    Purity: >98.00%

    MoTP는 특정 혈소판 활성화 인자 수용체 길항제이며 멜라닌 세포 제거를 유도할 수 있습니다. MoTP는 암 연구에 사용될 수 있습니다.

  • GC44250 structure
    GC44250MS351
    CAS: 472984-79-5
    Purity: >98.00%

    MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain.

  • GC44321 structure
    GC44321Nat-20(S)-yne
    CAS: 1397692-46-4
    Purity: >90.00%

    Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors.

  • GC44458 structure
    GC44458N-Palmitoyl-L-Aspartate
    CAS: 1782-17-8
    Purity: >98.00%

    N-Palmitoyl-L-aspartate is a natural N-acylaspartate that inhibits Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog.

  • GC44467 structure
    GC44467NSC 668036
    CAS: 144678-63-7
    Purity: >98.00%

    NSC 668036은 237μM의 Kd를 갖는 흐트러진(Dvl) PDZ 도메인 억제제입니다.

  • GC44612 structure
    GC44612PF-4800567
    CAS: 1188296-52-7
    Purity: >98.00%

    PF-4800567은 CK1δ(IC50, 711nM)에 비해 20배 이상 높은 IC50이 32nM인 카제인 키나제 1ε(CK1ε)의 강력하고 선택적인 억제제입니다.

  • GC44851 structure
    GC44851Rosiglitazone (potassium salt)
    CAS: 316371-84-3
    Purity: >98.00%

    Rosiglitazone(BRL 49653) 칼륨은 경구 활성 선택적 PPARγ입니다. 작용제(EC50: 60nM, Kd: 40nM).

  • GC44855 structure
    GC44855RU-SKI 43 (hydrochloride)
    CAS: 1782573-67-4
    Purity: >98.50%

    RU-SKI 43(염산염)은 IC50이 850nM인 강력하고 선택적인 고슴도치 아실트랜스퍼라제(Hhat) 억제제입니다. RU-SKI 43(염산염)은 Smoothened-independent non-canonical signaling을 통해 Gli-1 활성화를 감소시키고 Akt 및 mTOR 경로 활성을 감소시킵니다. RU-SKI 43(염산염)은 항암 활성이 있습니다.

  • GC45090 structure
    GC45090Triparanol
    CAS: 78-41-1
    Purity: >98.00%

    Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol.

  • GC45137 structure
    GC45137Valproic Acid Acyl-D-Glucuronide
    Purity: >95.00%

    Valproic acid acyl-D-glucuronide is the major urinary metabolite of valproic acid.

  • GC45354 structure
    GC453544β-Hydroxywithanolide E
    CAS: 54334-04-2
    Purity: >95.00%

    4β, Physalis peruviana L.에서 분리된 하이드록시위타놀라이드 E.

  • GC45482 structure
    GC45482Histone H3K9Me1 (3-17) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
    Purity: >95.00%

  • GC45596 structure
    GC45596YW1128
    CAS: 2131223-64-6
    Purity: >98.00%

    YW1128(화합물 3a)은 강력한 Wnt/β-카테닌 억제제입니다.

  • GC45597 structure
    GC45597YW1159
    CAS: 2131223-69-1
    Purity: >98.00%

  • GC46015 structure
    GC46015KY 05009
    CAS: 1228280-29-2
    Purity: >99.50%

    KY 05009는 100nM의 Ki를 갖는 ATP-경쟁적 Traf2 및 Nck-상호작용 키나제(TNIK) 억제제입니다. KY 05009는 인간 폐 선암종 세포에서 TGF-β1에 의해 유도된 상피에서 중간엽으로의 전이(EMT)를 약리학적으로 억제합니다. KY 05009는 TNIK의 단백질 발현과 Wnt 표적 유전자의 전사 활성을 억제하고 암세포에서 세포 사멸을 유도합니다. KY 05009는 항암 활성을 나타냅니다.

  • GC46939 structure
    GC46939BODIPY-aminoacetaldehyde diethyl acetal
    CAS: 247069-93-8
    Purity: >98.00%

    BODIPY-aminoacetaldehyde diethyl acetal (BAAA-DA)은 BODIPY-aminoacetaldehyde (BAAA)의 안정된 전이물로 세포를 관통할 수 있는 형광 전구체로서 알데하이드 드로게나이즈 (ALDH)를 탐지하는 데 사용되고 투과성 형광 파장이 488/512nm이다.

  • GC46947 structure
    GC46947BRD-K4477
    CAS: 2719-05-3
    Purity: >98.00%

    A small molecule promotor of hepatocyte differentiation

  • GC46986 structure
    GC46986C18 Ceramide-1-phosphate-d3 (d18:1/18:0-d3)
    CAS: 2692624-25-0
    Purity: >99.00%

    A neuropeptide with diverse biological activities