GLPBio

mGluR

The mGluR (metabotropic glutamate receptor) is a group C GPCR and is active through an indirect metabotropic process.

Products Related to mGluR (123)

  • GC10864 structure
    GC10864MPEP
    CAS: 96206-92-7
    Purity: >98.00%

    MPEP is a noncompetitive, selective, potent, orally active and systemically active mGlu5 receptor antagonist, with an IC 50 of 36nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis.

  • GC16619 structure
    GC16619CTEP (RO4956371)
    CAS: 871362-31-1
    Purity: >98.00%

    CTEP (RO4956371) (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist ofmGlu5receptor withIC50of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors.

  • GC17498 structure
    GC17498L-Glutamine
    CAS: 56-85-9
    Purity: >98.00%

    Non-essential amino acid

  • GC18087 structure
    GC18087VU 0357121
    CAS: 433967-28-3
    Purity: >99.50%

    Novel positive allosteric modulator (PAM) of mGlu5

  • GC10123 structure
    GC10123O-Phospho-L-serine
    CAS: 407-41-0
    Purity: >98.00%

    group III metabotropic glutamate receptor agonist

  • GC10494 structure
    GC10494ADX-47273
    CAS: 851881-60-2
    Purity: >99.00%

    mGluR5 receptor positive allosteric modulator, potent and selective

  • GC10605 structure
    GC10605LY 354740
    CAS: 176199-48-7
    Purity: >98.00%

    LY 354740 (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively.

  • GC11182 structure
    GC11182LY404039
    CAS: 635318-11-5
    Purity: >98.00%

    MGlu2 and mGlu3 receptors agonist

  • GC11459 structure
    GC11459Xanthurenic acid
    CAS: 59-00-7
    Purity: >98.00%

    Xanthurenic acid is an endogenous group II metabotropic glutamate receptor agonist involved in sensory transmission in the thalamus.

  • GC11501 structure
    GC11501TCN 238
    CAS: 125404-04-8
    Purity: >98.00%

    Positive allosteric modulator of mGlu4 receptors

  • GC11667 structure
    GC11667VU0483605
    CAS: 1623101-11-0
    Purity: >98%

    elective positive allosteric modulator (PAM) of mGluR1

  • GC11766 structure
    GC11766Fenobam
    CAS: 57653-26-6
    Purity: >99.50%

    mGlu5 antagonist

  • GC11871 structure
    GC11871MTEP hydrochloride
    CAS: 1186195-60-7
    Purity: >98.00%

    A selective mGlu5a receptor antagonist

  • GC11954 structure
    GC11954mGlu2 agonist
    CAS: 1311385-32-6
    Purity: >98.00%
  • GC11966 structure
    GC11966O-Phospho-D-Serine
    CAS: 73913-63-0
    Purity: >98%

    weak agonist of the metabotropic glutamate receptor mGluR4

  • GC12238 structure
    GC12238Oxomemazine
    CAS: 3689-50-7
    Purity: >98%

    NULL

  • GC12279 structure
    GC12279(RS)-MCPG
    CAS: 146669-29-6
    Purity: >99.50%

    mGluR antagonist

  • GC12394 structure
    GC12394(±)-trans-ACPD
    CAS: 67684-64-4
    Purity: >98.00%

    metabotropic glutamate receptors agonist

  • GC12485 structure
    GC12485Ro 67-7476
    CAS: 298690-60-5
    Purity: >99.50%

    positive allosteric modulator of mGlu1 receptors

  • GC12510 structure
    GC12510BINA
    CAS: 866823-73-6
    Purity: >99.00%

    BINA (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders.

  • GC12532 structure
    GC12532CHPG
    CAS: 170846-74-9
    Purity: >98.00%

    CHPG is a selective metabotropic glutamate receptor 5 (mGlu5) agonist.

  • GC12831 structure
    GC12831LY 367385
    CAS: 198419-91-9
    Purity: >99.00%

    mGlu1a receptor antagonist

  • GC13192 structure
    GC13192E4CPG
    CAS: 170846-89-6
    Purity: >98.00%

    group I/group II metabotropic glutamate receptor antagonist

  • GC13281 structure
    GC13281VU 0364770
    CAS: 61350-00-3
    Purity: >99.50%

    Positive allosteric modulator(PAM) of mGlu4