GLPBio

mGluR

The mGluR (metabotropic glutamate receptor) is a group C GPCR and is active through an indirect metabotropic process.

Products Related to mGluR (123)

  • GC13426 structure
    GC13426CPPHA
    CAS: 693288-97-0
    Purity: >98%

    A positive allosteric modulator of the mGluR5

  • GC13962 structure
    GC13962VU 0361737
    CAS: 1161205-04-4
    Purity: >99.50%

    MGlu4 receptor allosteric modulator

  • GC14036 structure
    GC14036ACPT-II
    CAS: 195209-04-2
    Purity: >98%

    metabotropic receptor antagonist

  • GC14555 structure
    GC14555LY341495
    CAS: 201943-63-7
    Purity: >98.50%

    Selective antagonist of mGluR2 and mGluR3

  • GC15992 structure
    GC15992Lu AF21934
    CAS: 1445605-23-1
    Purity: >99.00%

    positive allosteric modulator of mGlu4 receptors

  • GC16150 structure
    GC16150VU 0364439
    CAS: 1246086-78-1
    Purity: >98.50%

    Positive allosteric mGluR-4 modulator

  • GC16172 structure
    GC16172MPEP Hydrochloride
    CAS: 219911-35-0
    Purity: >98.00%

    MPEP Hydrochloride is a noncompetitive, selective, potent, orally active and systemically active mGlu5 receptor antagonist, with an IC 50 of 36nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis.

  • GC16349 structure
    GC16349(S)-MCPG
    CAS: 150145-89-4
    Purity: >98.50%

    mGluR antagonist

  • GC16523 structure
    GC16523Dipraglurant
    CAS: 872363-17-2
    Purity: >99.50%
  • GC17185 structure
    GC17185MSOP
    CAS: 66515-29-5
    Purity: >98.00%

    group III metabotropic glutamate receptor antagonist

  • GC17217 structure
    GC17217JNJ 16259685
    CAS: 409345-29-5
    Purity: >98.00%

    JNJ 16259685 is a potent and selective mGlu1 receptor antagonist with an IC 50 value of 19nM.

  • GC17383 structure
    GC17383PHCCC
    CAS: 179068-02-1
    Purity: >98.00%

    PHCCC is a group I mGluR antagonist with an IC 50 value of 3μM.

  • GC17401 structure
    GC17401RG7090
    CAS: 802906-73-6
    Purity: >98.00%

    RG7090 (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM.

  • GC17823 structure
    GC17823L-Cysteinesulfinic acid
    CAS: 1115-65-7
    Purity: >98.00%

    L-Cysteinesulfinic acid is an endogenous sulfur-containing excitatory amino acid, and an intermediate in the metabolic conversion of cysteine to taurine. L-Cysteinesulfinic acid acts as an agonist of NMDA receptors and mGlu receptors, and is applied in research on glutamatergic neurotransmission, taurine biosynthesis and central cardiovascular regulation.

  • GC17932 structure
    GC17932L-AP4
    CAS: 23052-81-5
    Purity: >99.00%

    group III metabotropic glutamate receptor agonist

  • GC17963 structure
    GC17963CHPG Sodium salt
    CAS: 1303993-73-8
    Purity: >99.50%

    CHPG Sodium salt is a selective metabotropic glutamate receptor 5 (mGlu5) agonist.

  • GC18120 structure
    GC18120XAP044
    CAS: 196928-50-4
    Purity: >98.00%

    XAP044 is a potent mGlu7 selective antagonist, with an IC 50 value of 5.5μM.

  • GC18412 structure
    GC18412VU0409551 (JNJ-46778212)
    CAS: 1363281-27-9
    Purity: >99.50%

    VU0409551 (JNJ-46778212) is a potent and selective biased positive allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu 5 PAM; EC 50 =260nM).

  • GC19207 structure
    GC19207JNJ-42153605
    CAS: 1254977-87-1
    Purity: >99.00%

    JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM.

  • GC19381 structure
    GC19381VU6005649
    CAS: 2137047-43-7
    Purity: >98.50%

    VU6005649 is a CNS penetrant mGlu7/8 receptor agonist with EC50s of 0.65 uM and 2.6 uM for mGlu7 receptor and mGlu8 receptor, respectively.

  • GC30224 structure
    GC30224FPTQ
    CAS: 864863-72-9
    Purity: >99.50%

    FPTQ is potent mGluR1 antagonist with IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively.

  • GC30303 structure
    GC30303Mavoglurant racemate (AFQ-056 racemate)
    CAS: 1636881-61-2
    Purity: >98.50%

    Mavoglurant racemate (AFQ-056 racemate) (AFQ-056 racemate) is the racemate of Mavoglurant.

  • GC30778 structure
    GC30778Mavoglurant (AFQ056)
    CAS: 543906-09-8
    Purity: >99.50%

    Mavoglurant (AFQ056) is a structurally selective, non-competitive, orally active antagonist of the metabotropic glutamate receptor 5 (mGluR5), with an IC 50 value of 30nM.

  • GC30793 structure
    GC30793ADX88178
    CAS: 1235318-89-4
    Purity: >99.50%

    ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.