MR837 is an inhibitor of NSD2-PWWP1. MR837 can bind with human nuclear receptor binding SET domain protein 2 (PWWP domain)[1].
MR837 is a NSD2-PWWP1 inhibitor[1].
[1]. Liu Y, et, al. PWWP1 domain of NSD2 in complex with MR837.
MR837
Catalog No.: GC61468Purity:>99.00%
MR837 is an inhibitor of NSD2-PWWP1. MR837 can bind with human nuclear receptor binding SET domain protein 2 (PWWP domain).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1210906-48-1
10mM (in 1mL DMSO)In Stock
$117.00
1
1mgIn Stock
$38.00
1
5mgIn Stock
$99.00
1
10mgIn Stock
$162.00
1
25mgIn Stock
$270.00
1
50mgIn Stock
$405.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $117.00 | In Stock | 1 | |
| 1mg | $38.00 | In Stock | 1 | |
| 5mg | $99.00 | In Stock | 1 | |
| 10mg | $162.00 | In Stock | 1 | |
| 25mg | $270.00 | In Stock | 1 | |
| 50mg | $405.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.00%Appearance:A solid
Chemical Properties
CAS No.
1210906-48-1
SMILES
O=C(N(C1CC1)CC2=CC=CS2)C3=CC=C(C#N)C=C3
Molecular Formula
C16H14N2OS
Molecular Weight
282.36
Solubility
Methanol: 125 mg/mL (442.70 mM); DMSO: 100 mg/mL (354.16 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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