GLPBio

PAR1

PAR1 (protease-activated receptor 1) is a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain.

Products Related to PAR1(43)

  • GC10140 structure
    GC10140Thrombin Receptor Agonist Peptide
    CAS: 137339-65-2
    Purity: >98%

    Thrombin Receptor Agonist Peptide is a synthetic thrombin receptor agonist peptide.

  • GC11662 structure
    GC11662TRAP-6
    CAS: 141136-83-6
    Purity: >99.50%

    TRAP-6 is a selective protease-activated receptor 1 (PAR1) agonist composed of six amino acids.

  • GC11727 structure
    GC11727VKGILS-NH2
    CAS: 942413-05-0
    Purity: >99.50%

    control peptide for SLIGKV-NH2, PAR1 agonist

  • GC11951 structure
    GC11951PAR 4 (1-6)
    CAS: 225779-44-2
    Purity: >98%

    PAR4 agonist

  • GC13227 structure
    GC13227LRGILS-NH2
    CAS: 245329-01-5
    Purity: >98%

    Protease-activated receptor agonist

  • GC14540 structure
    GC14540SLIGKV-NH2
    CAS: 190383-13-2
    Purity: >98.00%

    SLIGKV-NH2 (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

  • GC14831 structure
    GC14831AC 264613
    CAS: 1051487-82-1
    Purity: >95.00%

    PAR2 agonist,potent and selective

  • GC15290 structure
    GC15290AC 55541
    CAS: 916170-19-9
    Purity: >98.50%

    PAR2 agonist,potent and selective

  • GC15817 structure
    GC15817PAR-4 Agonist Peptide, amide (AY-NH2)
    CAS: 352017-71-1
    Purity: >98%

    PAR-4 Agonist Peptide, amide(AY-NH2) (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.

  • GC17368 structure
    GC173682-Furoyl-LIGRLO-amide
    CAS: 729589-58-6
    Purity: >99.50%

    Protease-activated receptor agonist

  • GC17444 structure
    GC17444TFLLR-NH2
    CAS: 197794-83-5
    Purity: >98%

    PAR1 selective agonist

  • GC17514 structure
    GC17514SLIGRL-NH2
    CAS: 171436-38-7
    Purity: >99.50%

    SLIGRL-NH2 is a specific protease-activated receptor 2 (PAR2) agonist with an EC 50 value of approximately 10μM. SLIGRL-NH2 does not activate PAR1.

  • GC17991 structure
    GC17991RLLFT-NH2
    CAS: 447408-68-6
    Purity: >98%

    Protease-activated receptor agonist

  • GA23350 structure
    GA23350PAR-3 (1-6) amide (human)
    CAS: 1872435-09-0
    Purity: >98%

    PAR-3 (1-6) amide (human) is a proteinase-activated receptor (PAR-3) agonist peptide.

  • GC10291 structure
    GC10291SCH 79797 dihydrochloride
    CAS: 1216720-69-2
    Purity: >98.00%

    SCH 79797 dihydrochloride is an efficient and selective non-peptide proteinase-activated receptor 1 (PAR1) antagonist, with an IC 50 of 70nM and a Ki of 35nM.

  • GC17545 structure
    GC17545Vorapaxar
    CAS: 618385-01-6
    Purity: >98.00%

    Vorapaxar is an orally active, selective, and competitive antagonist of the thrombin receptor protease-activated receptor (PAR-1), with a K d value of 1.27 ± 0.3nM. Its K i value increases as plasma concentration rises, reaching 39.2 nM at 100% plasma.

  • GC18152 structure
    GC18152AZ-3451
    CAS: 2100284-59-9
    Purity: >98.00%

    AZ-3451 is a protease-activated receptor-2 (PAR2) antagonist.

  • GC18717 structure
    GC18717BMS 986120
    CAS: 1478712-37-6
    Purity: >98.00%

    BMS 986120 is a compound specifically targeting protease-activated receptor 4 (PAR4), which comparably inhibited platelet aggregation (PA) induced by activation peptides selective for PAR4 (PAR4-AP) in human and monkey blood in vitro (IC 50 of 9.5±2.7 and 2.1±0.4nM, respectively).

  • GC33429 structure
    GC33429Protease-Activated Receptor-4
    CAS: 245443-52-1
    Purity: >98.00%

    Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

  • GC33599 structure
    GC33599PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA))
    CAS: 1228078-65-6
    Purity: >99.50%

    PAR-4 agonist peptide, amide TFA (PAR-4-AP (TFA)) is a synthetic peptide primarily used to activate protease-activated receptor 4 (PAR-4) .

  • GC36125 structure
    GC36125GB-110
    CAS: 1252806-70-4
    Purity: >98%

    GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.

  • GC37770 structure
    GC37770TFLLR-NH2(TFA)
    CAS: 1313730-19-6
    Purity: >99.50%

    TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM.

  • GC37852 structure
    GC37852UDM-001651
    CAS: 1477497-01-0
    Purity: >98%

    UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM).

  • GC38134 structure
    GC38134Parmodulin 2
    CAS: 423735-93-7
    Purity: >98%

    Reversible inhibitor of PAR1mediated platelet activation