Cardiovascular
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Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Research Areas
- Acute Phase Reactants(15)
- Angina(14)
- Arrhythmia(82)
- Atherosclerosis(88)
- Chronic Kidney Disease(18)
- Coagulation & Hemostasis(124)
- Coronary Artery Disease(7)
- Diabetic Nephropathy(8)
- Endothelium(33)
- Erythrocytes & Hemoglobin(49)
- Heart Failure(33)
- Hypertension(162)
- Hypotension(24)
- Lipoproteins(61)
- Myocardial Contractility(33)
- Myocardial Hypertrophy(21)
- Myocardial Infarction(61)
- Others(1)
- Serum Proteins(11)
- Smooth Muscle Cells(36)
- Storage & Transport(6)
- Stroke(48)
- Thrombosis(52)
- Vasoconstriction(59)
- Vasodilation(141)
- Cardiogenesis
- Cardiomyopathy(5)
- Cholesterol Metabolism(44)
Products Related to Cardiovascular(821)
- GC9110917β-Estradiol 3-O-Sulfate (sodium salt)CAS: 4999-79-5Purity: >98.00%
An inactive metabolite of 17β-estradiol
- GC91229DXR Inhibitor 11a (free acid)CAS: 2260608-07-7Purity: >98.00%
An inhibitor of P. falciparum DXR
- GC91424S1PL-IN-31CAS: 1538574-95-6Purity: >98.00%
S1PL-IN-31 is an inhibitor of sphingosine-1-phosphate (S1P) lyase (IC50 = 210 nM).
- GC91472Tat-Gap 19 (trifluoroacetate salt)Purity: >95.00%
Tat-Gap 19 is a peptide inhibitor of connexin43 (Cx43) hemichannels.
- GC91493Semaglutide Side ChainCAS: 1118767-16-0Purity: >98.00%
Semaglutide side chain is a synthetic intermediate.
- GC91497EB 47 (hydrochloride)CAS: 1190332-25-2Purity: >98.00%
EB 47 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 45 nM) and a dual site inhibitor of tankyrase 2 (TNKS2; IC50 = 45 nM).
- GC91544Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OHCAS: 1662688-20-1Purity: >99.50%
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide .
- GC91639Ferrous trisglycinateCAS: 34369-82-9Purity: >95.00%
Ferrous trisglycinate is an iron amino acid chelate.
- GC916804-Acetamido AntipyrineCAS: 83-15-8Purity: >95.00%
4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
- GC91889L-Tyrosine (sodium salt hydrate)Purity: >98.00%
L-Tyrosine is a conditionally essential amino acid.
- GC91910Ferroptosis Inhibitor D1Purity: >98.00%
Ferroptosis inhibitor D1 is a free radical scavenger and an inhibitor of ferroptosis.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC91053 | RM 133-3 | 2941228-90-4 | >95.00% | |
An ionizable cationic lipid | ||||
| GC91065 | (±)13,14-EDT | 355016-19-2 | >98.00% | |
A metabolite of adrenic acid | ||||
| GC91067 | (±)16,17-EDT | 351533-79-4 | >98.00% | |
A metabolite of adrenic acid | ||||
| GC91083 | Tiopronin-Cysteine Disulfide | 77591-18-5 | >95.00% | |
A metabolite of tiopronin | ||||
| GC91100 | UCL-TRO-1938 | 2919575-27-0 | >98.00% | |
An allosteric PI3Kα activator | ||||
| GC91109 | 17β-Estradiol 3-O-Sulfate (sodium salt) | 4999-79-5 | >98.00% | |
An inactive metabolite of 17β-estradiol | ||||
| GC91136 | XY-4 | 474329-47-0 | >95.00% | |
An agonist of PPARγ | ||||
| GC91141 | DXR Inhibitor 11a (sodium salt) | - | >98.00% | |
An inhibitor of P. falciparum DXR | ||||
| GC91223 | Brain Natriuretic Peptide-32 (rat) (acetate) | - | >98.00% | |
A natriuretic peptide | ||||
| GC91229 | DXR Inhibitor 11a (free acid) | 2260608-07-7 | >98.00% | |
An inhibitor of P. falciparum DXR | ||||
| GC91410 | RA-2 | 1867107-62-7 | >95.00% | |
RA-2 is an inhibitor of small-conductance calcium-activated potassium channel 2.3 (KCa2.3/SK3) and intermediate-conductance calcium-activated potassium channel 3.1 (KCa3.1/IK1) (IC50s = 2 and 17 nM, respectively). | ||||
| GC91424 | S1PL-IN-31 | 1538574-95-6 | >98.00% | |
S1PL-IN-31 is an inhibitor of sphingosine-1-phosphate (S1P) lyase (IC50 = 210 nM). | ||||
| GC91472 | Tat-Gap 19 (trifluoroacetate salt) | - | >95.00% | |
Tat-Gap 19 is a peptide inhibitor of connexin43 (Cx43) hemichannels. | ||||
| GC91493 | Semaglutide Side Chain | 1118767-16-0 | >98.00% | |
Semaglutide side chain is a synthetic intermediate. | ||||
| GC91497 | EB 47 (hydrochloride) | 1190332-25-2 | >98.00% | |
EB 47 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 45 nM) and a dual site inhibitor of tankyrase 2 (TNKS2; IC50 = 45 nM). | ||||
| GC91544 | Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH | 1662688-20-1 | >99.50% | |
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide . | ||||
| GC91615 | AZD 5462 | 2787501-83-9 | >98.00% | |
AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1). | ||||
| GC91639 | Ferrous trisglycinate | 34369-82-9 | >95.00% | |
Ferrous trisglycinate is an iron amino acid chelate. | ||||
| GC91680 | 4-Acetamido Antipyrine | 83-15-8 | >95.00% | |
4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole . | ||||
| GC91889 | L-Tyrosine (sodium salt hydrate) | - | >98.00% | |
L-Tyrosine is a conditionally essential amino acid. | ||||
| GC91898 | BI SF3 (hydrochloride) | 1801257-24-8 | >95.00% | |
BI SF3 is a synthetic intermediate. | ||||
| GC91910 | Ferroptosis Inhibitor D1 | - | >98.00% | |
Ferroptosis inhibitor D1 is a free radical scavenger and an inhibitor of ferroptosis. | ||||
| GC91915 | ZG-2033 | 2685739-28-8 | >98.00% | |
ZG-2033 is an agonist of hypoxia-inducible factor 2α (HIF-2α). | ||||
| GC91933 | E17241 | 1060968-92-4 | >95.00% | |
E17241 is an inducer of the expression of ABCA1, the gene encoding ATP-binding cassette transporter 1; subfamily A (ABCA1). | ||||
