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Home >> Signaling Pathways >> Cardiovascular >> Myocardial Contractility

Myocardial Contractility

Products for  Myocardial Contractility

  1. Cat.No. Product Name Information
  2. GC41661 (±)-4-hydroxy Propranolol β-D-Glucuronide (±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol. (±)-4-hydroxy Propranolol β-D-Glucuronide Chemical Structure
  3. GC46304 (±)-Nebivolol-d4 (hydrochloride) A neuropeptide with diverse biological activities (±)-Nebivolol-d4 (hydrochloride) Chemical Structure
  4. GC42409 4-hydroxy Nebivolol (hydrochloride) 4-hydroxy Nebivolol is a major metabolite of nebivolol. 4-hydroxy Nebivolol (hydrochloride) Chemical Structure
  5. GC42548 5-hydroxy Saxagliptin (hydrochloride) 5-hydroxy Saxagliptin is a major active metabolite of saxagliptin. 5-hydroxy Saxagliptin (hydrochloride) Chemical Structure
  6. GC18474 Acetyldigitoxin Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. Acetyldigitoxin Chemical Structure
  7. GC91615 AZD 5462 AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1). AZD 5462 Chemical Structure
  8. GC18716 Bisindolylmaleimide XI (hydrochloride)

    BIM XI, Ro 310432

     Bisindolylmaleimide XI (BIM XI) is a selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over Ca2+-independent PKCε (IC50 = 108 nM). Bisindolylmaleimide XI (hydrochloride) Chemical Structure
  9. GC43062 C2 Ceramide (d14:1/2:0)

    Cer(d14:1/2:0), Ceramide (d14:1/2:0), N-acetyl-D-erythro-Sphingosine C14

    C2 Ceramide (d14:1/2:0) is a bioactive sphingolipid.

     C2 Ceramide (d14:1/2:0) Chemical Structure
  10. GC41449 Carbazeran Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3. Carbazeran Chemical Structure
  11. GC49197 Carbinoxamine-d6 (maleate) An internal standard for the quantification of carbinoxamine Carbinoxamine-d6 (maleate) Chemical Structure
  12. GC18879 CAY10662 17(R),18(S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EpETE), a natural cytochrome P450 epoxygenase metabolite of eicosapentaenoic acid, is known to reduce the contraction rate of spontaneously beating heart cells and to protect neonatal rat cardiomyocytes against arrhythmias induced by β-adrenergic agonists (EC50 = ~ 1-2 nM). CAY10662 Chemical Structure
  13. GC18698 CAY10665 Isolated neonatal rat cardiomyocytes, which spontaneously beat in culture, are used to evaluate the antiarrhythmic effects of polyunsaturated fatty acids (PUFA). CAY10665 Chemical Structure
  14. GC60120 Danicamtiv

    MYK-491, SAR440181

    Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.

     Danicamtiv Chemical Structure
  15. GC41485 Digitoxigenin

    Cerberigenin, (+)-Digitoxigenin, Echujetin, Evonogenin, NSC 407806, Thevetigenin, Δ20:22-3,14,21-Trihydroxynorcholenic acid lactone

     Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D. Digitoxigenin Chemical Structure
  16. GC49842 Digoxigenin Bisdigitoxoside

    Bisdigoxigenin

     A Na+/K+-ATPase inhibitor Digoxigenin Bisdigitoxoside Chemical Structure
  17. GC18455 Digoxigenin Monodigitoxoside Digoxigenin monodigitoxoside is a Na+/K+-ATPase inhibitor and cardiac glycoside metabolite of digoxin . Digoxigenin Monodigitoxoside Chemical Structure
  18. GC43565 Doxorubicinol (hydrochloride)

    13-Dihydroadriamycin hydrochloride

     Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. Doxorubicinol (hydrochloride) Chemical Structure
  19. GC52035 Esmolol Acid (hydrochloride)

    ASL 8123

     An active metabolite of esmolol Esmolol Acid (hydrochloride) Chemical Structure
  20. GC47307 Esmolol-d7 (hydrochloride) An internal standard for the quantification of esmolol Esmolol-d7 (hydrochloride) Chemical Structure
  21. GC49250 Hydroxydehydro Nifedipine Carboxylate A metabolite of nifedipine Hydroxydehydro Nifedipine Carboxylate Chemical Structure
  22. GC45728 Iohexol-d5 An internal standard for the quantification of iohexol Iohexol-d5 Chemical Structure
  23. GC44013 KR-32568 KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). KR-32568 Chemical Structure
  24. GC47597 Manidipine-d4

    Franidipine-d4, (±)-Manidipine-d4

     An internal standard for the quantification of manidipine Manidipine-d4 Chemical Structure
  25. GC40231 Milrinone-d3 Milrinone-d3 is intended for use as an internal standard for the quantification of milrinone by GC- or LC-MS. Milrinone-d3 Chemical Structure
  26. GC44358 Nebivolol O-β-D-Glucuronide Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol. Nebivolol O-β-D-Glucuronide Chemical Structure
  27. GC44384 Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)

    NPY (3-36) (human, rat)

     Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt) Chemical Structure
  28. GC52019 Norpropranolol (hydrochloride)

    (±)-Desisopropylpropranolol, N-Desisopropylpropranolol

     An active metabolite of propranolol Norpropranolol (hydrochloride) Chemical Structure
  29. GC49024 Palmitic Acid MaxSpec® Standard

    C16:0, Cetylic Acid, NSC 5030

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  30. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    C16:0-d9, Cetylic Acid-d9

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  31. GC44699 Propranolol β-D-Glucuronide (sodium salt) Propranolol β-D-glucuronide is a major metabolite of propranolol. Propranolol β-D-Glucuronide (sodium salt) Chemical Structure
  32. GC45903 Quazinone

    Ro 13-6438

     A PDE3 inhibitor Quazinone Chemical Structure
  33. GC44803 rac-7-hydroxy Propranolol (hydrochloride)

    (±)-7-hydroxy Propranolol

     rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol). rac-7-hydroxy Propranolol (hydrochloride) Chemical Structure
  34. GC48069 Saxagliptin-13C-d2 (hydrochloride) A neuropeptide with diverse biological activities Saxagliptin-13C-d2 (hydrochloride) Chemical Structure
  35. GC45096 Tyr-α-CGRP (human) (trifluoroacetate salt)

    Tyr0-CGRP (human)

     Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide. Tyr-α-CGRP (human) (trifluoroacetate salt) Chemical Structure

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