Vasodilation
Products for Vasodilation
- Cat.No. Product Name Information
-
GC45200
α-CGRP (rat) (trifluoroacetate salt)
Calcitonin Gene-Related Peptide-1 (rat), α-Calcitonin Gene-Related Peptide (rat), CGRP-1 (rat)
α-Calcitonin gene-related peptide (α-CGRP) is a neuropeptide with roles in vasodilation, cardiovascular regulation, and inflammation. -
GC45602
α-Linolenic Acid-d5 MaxSpec• Standard
ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5
-
GC40105
βARK1 Inhibitor
βARK1 Inhibitor (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor.
-
GC41661
(±)-4-hydroxy Propranolol β-D-Glucuronide
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
-
GC46304
(±)-Nebivolol-d4 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC90022
(±)-Norepinephrine-d6 (hydrochloride)
An internal standard for the quantification of norepinephrine
-
GC46312
(±)-Verapamil-d3 (hydrochloride)
(±)-Verapamil-d3 hydrochloride; CP-16533-1-d3 hydrochloride
A neuropeptide with diverse biological activities -
GC40386
(±)11(12)-EpETE
(±)11,12-EEQ, (±)11,12-Epoxyeicosatetraenoic Acid
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms. -
GC91065
(±)13,14-EDT
A metabolite of adrenic acid
-
GC40430
(±)14(15)-EET
(±)14,15-EET, (±)14,15-EpETrE
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.
-
GC40835
(±)14(15)-EET methyl ester
(±)14,15EpETrE methyl ester
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC41651
(±)14(15)-EET-SI
14,15-EpETrE-SI, 14(15)-EET-SI, 14(15)EETsulfonimide
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. -
GC91067
(±)16,17-EDT
A metabolite of adrenic acid
-
GC41288
(±)17(18)-EpETE-Ethanolamide
17,18-EEQ-EA, (±)17,18-EEQ-Ethanolamide, (±)17(18)-EpETE-EA, 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. -
GC40436
(±)18-HETE
(±)18-Hydroxyeicosatetraenoic Acid
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. -
GC41655
(±)19(20)-EDP Ethanolamide
19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). -
GC40437
(±)5(6)-DiHET lactone
(±)5,6DiHETrE lactone
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. -
GC40438
(±)5(6)-EET
(±)5,6EpETrE
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. -
GC40421
(±)8(9)-EE-14(Z)-E
(±)8,9-Epoxyeicosa-14(Z)-enoic Acid
(±)14(15)-EE-8(Z)-E is a potent vasodilator in bovine coronary arteries. -
GC41697
(Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt)
AY-NH2, AYPGKF-NH2, H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2, PAR4-AP, Proteinase-Activated Receptor 4 Activating Peptide
(Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively). -
GC18637
11β-Prostaglandin F2α
9α,11βPGF2α, 11βPGF2α, 11epi PGF2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
-
GC46425
13,14-dihydro-15-keto Prostaglandin E1-d4
13,14dh15k PGE1d4
A neuropeptide with diverse biological activities -
GC40425
14,15-EE-8(Z)-E
14,15Epoxyeicosa8(Z)enoic Acid
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. -
GC46438
14S(15R)-EET
14S,15R-EpETrE
A cytochrome P450 metabolite of arachidonic acid -
GC91109
17β-Estradiol 3-O-Sulfate (sodium salt)
An inactive metabolite of 17β-estradiol
-
GC40457
19(R)-HETE
19(R)-Hydroxyeicosatetraenoic Acid
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. -
GC90840
2-Chloroadenosine-5'-O-diphosphate (sodium salt)
A derivative of ADP
-
GC42160
2-furoyl-LIGRLO amide (trifluoroacetate salt)
2-furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0).
-
GC40503
2-HOBA
2-(Aminomethyl)phenol, 2-Hydroxybenzylamine, NSC 127870
2-HOBA (2-HOBA) a selective dicarbonyl scavenger, is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). -
GC41104
20-carboxy Arachidonic Acid
20carboxy AA, 20COOHAA
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. -
GC42409
4-hydroxy Nebivolol (hydrochloride)
4-hydroxy Nebivolol is a major metabolite of nebivolol.
-
GC46708
5'-N-Ethylcarboxamidoadenosine (hydrate)
Adenosine 5'-ethylcarboxamide, NECA
A neuropeptide with diverse biological activities -
GC40336
5-cis Carbaprostacyclin
(5Z)6aCarbaprostaglandin I2
5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. -
GC40586
6β-Prostaglandin I1
6βPGI1, 5,6βdihydro PGI2
6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. -
GC18820
6-keto Prostaglandin E1
6keto PGE1
6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes. -
GC49576
Abnormal Cannabidiol-d3
Abn-CBD-d3, o-CBD, ortho-Cannabidiol
Internal standard for the quantification of abnormal cannabidiol -
GC42739
Adrenomedullin (1-50) amide (rat) (trifluoroacetate salt)
Adrenomedullin (1-50) is a peptide hormone with RNA expressed in rat adrenal glands, lung, kidney, heart, and spleen, as well as in the duodenum and submandibular glands.
-
GC42740
Adrenomedullin (1-52) (human) (trifluoroacetate salt)
Adrenomedullin (1-52)-NH2
Adrenomedullin (1-52) is a peptide with diverse biological activities. -
GC40158
Adrenomedullin (11-50) (rat) (trifluoroacetate salt)
Adrenomedullin (11-50) is a truncated form of rat adrenomedullin.
-
GC42738
Adrenomedullin (13-52) (human) (trifluoroacetate salt)
Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52).
-
GC42746
AFP 07 (free acid)
Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.
-
GC52023
Alfuzosin-d7
SL 77499-10-d7, Uroxatral-d7
An internal standard for the quantification of alfuzosin -
GC42778
Amauromine
Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM.
-
GC49638
Ambrisentan-d3
An internal standard for the quantification of ambrisentan
-
GC46856
Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin (5-8)
An endogenous angiotensin II fragment
-
GC52427
Apelin-12 (human, mouse, rat, bovine) (acetate)
RPRLSHKGPMPF
An endogenous agonist of the APJ receptor -
GC49314
Arecaidine propargyl ester (hydrobromide)
APE
A muscarinic M2 agonist -
GC49057
Azelastine-13C-d3 (hydrochloride)
An internal standard for the quantification of azelastine
-
GC18313
BAR501 Impurity
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1).
-
GC52145
Bradykinin (human, mouse, rat, bovine) (acetate)
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, BK, RPPGFSPFR-OH
-
GC49880
Bradykinin (trifluoroacetate salt)
An endogenous vasodilator
-
GC52424
Bradykinin Fragment (1-5) (trifluoroacetate salt)
Arg-Pro-Pro-Gly-Phe, BK1-5, RPPGF
A metabolite of bradykinin -
GC42970
Brain Natriuretic Peptide (1-32) (human) (trifluoroacetate salt)
BNP (1-32) (human)
Brain natriuretic peptide (BNP) (1-32) is an endogenous peptide that has cardiovascular functions and belongs to the family of natriuretic peptides, which includes atrial natriuretic peptide and C-type natriuretic peptide. -
GC91223
Brain Natriuretic Peptide-32 (rat) (acetate)
A natriuretic peptide
-
GC43328
C-Type Natriuretic Peptide-22 (human, porcine, rat) (trifluoroacetate salt)
CNP-22
C-Type natriuretic peptide-22 (CNP-22) is an endogenous peptide with diverse biological activities. -
GC47021
Caloxin 2A1 (trifluoroacetate salt)
VSNSNWPSFPSSGGG-NH2
A neuropeptide with diverse biological activities -
GC47045
Carvedilol-d5
An internal standard for the quantification of carvedilol
-
GC41381
CAY10562
4phenyl1,3,2Oxathiazolylium5olate
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. -
GC52006
CB-096
An inhibitor of RAN translation
-
GC47100
Clevidipine-d7
rac-Clevidipine-d7
A neuropeptide with diverse biological activities -
GC47103
Clonidine-d4 (hydrochloride)
An internal standard for the quantification of clonidine
-
GC43399
Dehydro Amlodipine (fumarate)
Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine.
-
GC43405
Dehydroevodiamine (hydrochloride)
Dehydroevodiamine is an alkaloid that has been isolated from E.
-
GC49866
Desmethyl Carvedilol
BM 14242, O-desmethyl Carvedilol
An active metabolite of carvedilol -
GC46131
Diazoxide-d3
An internal standard for the quantification of diazoxide
-
GC45427
Dihydrolycorine
-
GC49497
Dopamine-d4 (hydrochloride)
DA-d4, 3-hydroxy Tyramine-d4
An internal standard for the quantification of dopamine -
GC47268
Doxazosin-d8 (hydrochloride)
An internal standard for the quantification of doxazosin
-
GC43601
Enalaprilat (hydrate)
Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension.
-
GC20107
Fendiline hydrochloride
Fendiline hydrochloride is a nonselective calcium channel blocker.
-
GC45761
Flupirtine-d4 (hydrochloride)
D 9998-d4 hydrochloride
An internal standard for the quantification of flupirtine -
GC47371
Fosinopril-d7 (sodium salt)
An internal standard for the quantification of fosinopril
-
GC49089
FR900359
UBO-QIC
FR900359 is an inhibitor of G proteins Gαq, Gα11, and Gα14 with IC50 values of 13.18, 10.47, and 10nM, respectively and is isolated from the leaves of the ornamental plant Ardisia crenata -
GC49117
Guanadrel
An antihypertensive agent
-
GC47418
Gymnoascolide A
A fungal metabolite with fungicidal and vasodilatory activities
-
GC46155
H-Ile-Pro-Pro-OH (trifluoroacetate salt)
IPP
A neuropeptide with diverse biological activities -
GC47438
H-Val-Pro-Pro-OH (trifluoroactetate salt)
VPP
A neuropeptide with diverse biological activities -
GC43802
HA-1004 (hydrochloride)
HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively).
-
GC43803
HA-1077 (hydrochloride)
Fasudil
Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. HA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator. -
GC49882
Hemokinin 1 (human) (trifluoroacetate salt)
HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2
A peptide agonist of NK1 receptors -
GC47439
Hydralazine-d4 (hydrochloride)
1-Hydrazinophthalazine-d4
A neuropeptide with diverse biological activities -
GC49343
Isoproterenol-d7 (hydrochloride)
Isoprenaline-d7
An internal standard for the quantification of isoproterenol -
GC47471
Isoxsuprine-d6 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC52310
L-Arginine-13C6 (hydrochloride)
L-(+)-Arginine-13C6
An internal standard for the quantification of L-arginine -
GC49374
L-Arginine-d7 (hydrochloride)
L-(+)-Arginine-d7
An internal standard for the quantification of L-arginine -
GC44062
L-hydroxy Arginine (acetate)
L-NG-hydroxy Arginine, N5-hydroxy L-Arginine, Nω-hydroxy-L-Arginine
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. -
GC40239
Limaprost-d3
17α,20-dimethyl-Δ2-PGE1-d3, 17α,20-dimethyl-Δ2-Prostaglandin E1-d3
Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS. -
GC47585
Lys-(Des-Arg9)-Bradykinin (trifluoroacetate salt)
(Des-Arg10)-Kallidin, (Des-Arg10)-KD, KRPPGFSPF-OH, Lys-(Des-Arg9)-BK, N2-L-lysyl-9-de-L-arginine-Bradykinin
A neuropeptide with diverse biological activities -
GC49916
Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt)
Des-Arg10,Leu9-Kallidin, Des-Arg10,Leu9-KD, LysLeu8Des-Arg9-BK, LysLeu8Des-Arg9-Bradykinin
A bradykinin B1 receptor antagonist -
GC40231
Milrinone-d3
Milrinone-d3 is intended for use as an internal standard for the quantification of milrinone by GC- or LC-MS.
-
GC47679
Minoxidil-d10
Loniten-d10, U-10858-d10
An internal standard for the quantification of minoxidil -
GC92012
MT-1207 (hydrochloride)
MT-1207 is an orally active and selective adrenergic α1 and 5-HT2A receptor antagonist. MT-1207 shows IC50<0.1 nM, 0.15 nM, 1.40 nM and 0.27 nM for α1A, α1B, α1D and 5-HT2A, respectively.
-
GC44320
N-Arachidonoyl-L-Serine
ARA-S
Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature. -
GC49683
N-desethyl-N-methyl Vardenafil
A potential impurity found in commercial preparations of vardenafil
-
GC52045
N-desmethyl Azelastine
DAZ, Desmethylazelastine
N-desmethyl Azelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours. -
GC52132
N-desmethyl Diltiazem (hydrochloride)
-
GC44351
N-Desmethyl Sildenafil (citrate)
N-Desmethyl sildenafil is a major metabolite of sildenafil.
-
GC48584
Naftopidil-d5
KT-611-d5; BM-15275-d5
-
GC44358
Nebivolol O-β-D-Glucuronide
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.
-
GC49301
Nesiritide (acetate)
A natriuretic peptide