Dopamine Receptor
Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.
Products Related to Dopamine Receptor(300)
- GC39237PerospironeCAS: 150915-41-6Purity: >99.50%
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM).
- GC39724Quetiapine D4 hemifumarateCAS: 1217310-65-0Purity: >98%
Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate.
- GC39736Propionylpromazine hydrochlorideCAS: 7681-67-6Purity: >99.00%
Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease.
- GC39757Etilevodopa hydrochlorideCAS: 39740-30-2Purity: >98.50%
Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract.
- GC43660Fenoldopam (mesylate)CAS: 67227-57-0Purity: >99.50%
Fenoldopam is an agonist of dopamine D1A (D1R) and D1B (D5R) receptors (Kds = 17 and 11 nM, respectively).
- GC45188ZuclopenthixolCAS: 53772-83-1Purity: >98.00%
Zuclopenthixol is a dopamine receptor antagonist (Kis = 9.8 and 1.5 nM for D1 and D2 receptors, respectively).
- GC45756Pimozide-d4CAS: 1803193-57-8Purity: >99.00%
An internal standard for the quantification of pimozide
- GC46007Cariprazine-d6CAS: 1308278-67-2Purity: >99.00%
An internal standard for the quantification of cariprazine
- GC47101Clomipramine-d3 (hydrochloride)CAS: 1398065-86-5Purity: >99.50%
An Analytical Reference Standard
- GC50027Xaliproden hydrochlorideCAS: 90494-79-4Purity: >99.00%
High affinity 5-HT1A agonist; orally active
- GC50193Clozapine - d8CAS: 1185053-50-2Purity: >98%
Clozapine - d8 (HF 1854-d8) is the deuterium labeled Clozapine.
- GC600172'-O-MethylisoliquiritigeninCAS: 51828-10-5Purity: >98.00%
2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway.
- GC60334SB-277011 hydrochlorideCAS: 215804-67-4Purity: >99.50%
SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate?dopamine D3?receptor (D3R)?antagonist with Ki values of 10.7?nM and?11.2 nM?at?rodent and human?D3R, respectively.
- GC605053-O-MethyldopaCAS: 300-48-1Purity: >98.00%
3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT).
- GC605063-O-Methyldopa D3CAS: 586954-09-8Purity: >99.00%
3-O-Methyldopa D3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa.
- GC60662Brexpiprazole S-oxideCAS: 1191900-51-2Purity: >96.50%
Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4).
- GC60915Hydroxy ziprasidoneCAS: 884305-08-2Purity: >98%
Hydroxy ziprasidone is an impurity of Ziprasidone.
- GC61167Paliperidone palmitateCAS: 199739-10-1Purity: >98.00%
Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone.
- GC61389Ziprasidone amino acidCAS: 1159977-64-6Purity: >98%
Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC39237 | Perospirone | 150915-41-6 | >99.50% | |
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). | ||||
| GC39724 | Quetiapine D4 hemifumarate | 1217310-65-0 | >98% | |
Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. | ||||
| GC39736 | Propionylpromazine hydrochloride | 7681-67-6 | >99.00% | |
Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease. | ||||
| GC39757 | Etilevodopa hydrochloride | 39740-30-2 | >98.50% | |
Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. | ||||
| GC43660 | Fenoldopam (mesylate) | 67227-57-0 | >99.50% | |
Fenoldopam is an agonist of dopamine D1A (D1R) and D1B (D5R) receptors (Kds = 17 and 11 nM, respectively). | ||||
| GC45188 | Zuclopenthixol | 53772-83-1 | >98.00% | |
Zuclopenthixol is a dopamine receptor antagonist (Kis = 9.8 and 1.5 nM for D1 and D2 receptors, respectively). | ||||
| GC45676 | MLS-1547 | 315698-36-3 | >98.00% | |
MLS-1547 is a potent and G protein-biased agonist of the dopamine D2 receptor (D2R), exhibiting an EC 50 value of 0.37nM and an E max of approximately 90% in a D2R-mediated D2-Gqi5 calcium mobilization assay. | ||||
| GC45756 | Pimozide-d4 | 1803193-57-8 | >99.00% | |
An internal standard for the quantification of pimozide | ||||
| GC46007 | Cariprazine-d6 | 1308278-67-2 | >99.00% | |
An internal standard for the quantification of cariprazine | ||||
| GC47101 | Clomipramine-d3 (hydrochloride) | 1398065-86-5 | >99.50% | |
An Analytical Reference Standard | ||||
| GC50018 | Fenoldopam hydrochloride | 181217-39-0 | >98% | |
Selective D1-like partial agonist | ||||
| GC50027 | Xaliproden hydrochloride | 90494-79-4 | >99.00% | |
High affinity 5-HT1A agonist; orally active | ||||
| GC50193 | Clozapine - d8 | 1185053-50-2 | >98% | |
Clozapine - d8 (HF 1854-d8) is the deuterium labeled Clozapine. | ||||
| GC50644 | SK 609 | 1092797-77-7 | >98% | |
Dopamine D3 receptor biased agonist | ||||
| GC60017 | 2'-O-Methylisoliquiritigenin | 51828-10-5 | >98.00% | |
2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway. | ||||
| GC60334 | SB-277011 hydrochloride | 215804-67-4 | >99.50% | |
SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate?dopamine D3?receptor (D3R)?antagonist with Ki values of 10.7?nM and?11.2 nM?at?rodent and human?D3R, respectively. | ||||
| GC60505 | 3-O-Methyldopa | 300-48-1 | >98.00% | |
3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). | ||||
| GC60506 | 3-O-Methyldopa D3 | 586954-09-8 | >99.00% | |
3-O-Methyldopa D3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa. | ||||
| GC60662 | Brexpiprazole S-oxide | 1191900-51-2 | >96.50% | |
Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). | ||||
| GC60915 | Hydroxy ziprasidone | 884305-08-2 | >98% | |
Hydroxy ziprasidone is an impurity of Ziprasidone. | ||||
| GC60965 | Keto Ziprasidone | 884305-07-1 | >98% | |
Keto Ziprasidone is an impurity of Ziprasidone. | ||||
| GC61167 | Paliperidone palmitate | 199739-10-1 | >98.00% | |
Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. | ||||
| GC61281 | SKF-83566 | 99295-33-7 | >99.00% | |
SKF-83566 is a potent,?blood-brain permeable and orally active D1-like dopamine receptor (D1DR)?antagonist and a weaker competitive antagonist at the vascular 5-HT2?receptor (Ki=11 nM). | ||||
| GC61389 | Ziprasidone amino acid | 1159977-64-6 | >98% | |
Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. | ||||