Dipraglurant |
| Catalog No.GC16523 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 872363-17-2
Sample solution is provided at 25 µL, 10mM.
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Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1]Target: mGluRDipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.
References:
[1]. The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12
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