GLPBio

Ferroptosis

Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.

Products Related to Ferroptosis(211)

  • GC90713 structure
    GC90713FSEN1
    CAS: 862808-01-3
    Purity: >95.00%

    An inhibitor of FSP1

  • GC90714 structure
    GC90714LOC1886
    CAS: 951948-38-2
    Purity: >95.00%

    A GPX4 inhibitor

  • GC90827 structure
    GC90827GPX4 24
    Purity: >98.00%

    A GPX4 inhibitor

  • GC91157 structure
    GC91157C18
    CAS: 2922824-09-5
    Purity: >98.00%

    A covalent GPX4 inhibitor

  • GC91380 structure
    GC91380N6F11
    CAS: 851398-76-0
    Purity: >99.50%

    N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.

  • GC91598 structure
    GC91598GPX4 16
    CAS: 2644044-43-7
    Purity: >98.00%

    GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4).

  • GC91613 structure
    GC91613FerroLOXIN-1
    CAS: 2773428-48-9
    Purity: >90.00%

    FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.

  • GC91623 structure
    GC91623Ferroptosis Inducer 24
    CAS: 28657-88-7
    Purity: >95.00%

    Ferroptosis inducer 24 is an inducer of ferroptosis.

  • GC91691 structure
    GC91691viFSP1
    CAS: 951945-67-8
    Purity: >95.00%

    viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).

  • GC91783 structure
    GC91783FA16
    Purity: >95.00%

    FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.

  • GC91910 structure
    GC91910Ferroptosis Inhibitor D1
    Purity: >98.00%

    Ferroptosis inhibitor D1 is a free radical scavenger and an inhibitor of ferroptosis.

  • GC92031 structure
    GC92031GPX4 Inhibitor 17
    Purity: >98.00%

    GPX4 inhibitor 17 is a ferrocene-containing inhibitor of glutathione peroxidase 4 (GPX4) and an inducer of ferroptosis.

  • GF15486 structure
    GF15486Cathepsin B from bovine spleen
    CAS: 9047-22-7

    Cathepsin B from bovine spleen (Cathepsin B) is a member of the cysteine protease papain-like family. Cathepsin B is synthesized as a preproenzyme consisting of 335 amino acids, with a calculated molecular weight of approximately 36.7kDa. Cathepsin B is localized in the endosomal/lysosomal compartment, where Cathepsin B functions as both an endopeptidase and an exopeptidase. Cathepsin B primarily participates in the routine turnover of intracellular and extracellular proteins, thereby maintaining the homeostatic metabolic activity within the cell.

  • GN10158 structure
    GN10158Baicalein
    CAS: 491-67-8
    Purity: >98.00%

    Baicalein (5,6,7-trihydroxyflavone) is a flavonoid compound with multiple biological activities. It is a xanthine oxidase inhibitor with an IC 50 value of 3.12μM.

  • GN10289 structure
    GN10289Trigonelline
    CAS: 535-83-1
    Purity: >99.50%

    Trigonelline, an alkaloid isolated from Trigonella foenum-graecum L or Leonurus artemisia , is a potent and specific inhibitor of Nrf2.

  • GN10361 structure
    GN10361Pseudolaric Acid B
    CAS: 82508-31-4
    Purity: >98.00%
  • GN10388 structure
    GN10388Gallic acid
    CAS: 149-91-7
    Purity: >99.00%

    Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities.

  • GN10647 structure
    GN10647Artemisinine
    CAS: 63968-64-9
    Purity: >98.00%

    Artemisinine is a sesquiterpene lactone antimalarial drug extracted from the plant Artemisia annua .

  • GN10668 structure
    GN10668Coenzyme Q10
    CAS: 303-98-0
    Purity: >98.00%