Ferroptosis

WJ460 is a potent myoferlin (MYOF) inhibitor, which interacts directly with MYOF.

A precursor to artemisinin

UAMC-3203 is an inhibitor of ferroptosis that has an IC50 value of 10 nM for inhibition of erastin-induced ferroptosis in IMR-32 neuroblastoma cells.

Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1.

Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin by GC- or LC-MS.

Fluvastatin-d6 is intended for use as an internal standard for the quantification of fluvastatin by GC- or LC-MS.

SRS11-92 is a ferroptosis inhibitor and a derivative of ferrostatin-1.

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides.

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.

BHT is an antioxidant widely used in foods and in food-related products. BHT is a Ferroptosis inhibitor.

Cerivastatin (sodium salt) is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L.

Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.

The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals.

Erastin2 is a potent system xc- inhibitor and ferroptosis-inducing agent.

ML-162 is a small molecule that inhibits Glutathione peroxidase 4 (GPX4), with an IC 50 value of 1.42µM.

Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM).

Siramesine is an agonist of the sigma-2 (σ2) receptor (IC50 = 0.19 nM).

SRS16-86 is a third-generation ferrostatin-class ferroptosis inhibitor.

(-)-FINO2 is an organic peroxide that can selectively induce ferroptosis and is used to study the mechanisms of ferroptosis and anticancer therapy.

A neuropeptide with diverse biological activities

An inducer of ferroptosis