Ferroptosis
Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.
Products Related to Ferroptosis(211)
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9Purity: >98.00%
Imidazole Ketone Erastin is an effective and metabolically stable system xc- inhibitor and ferroptosis inducer.
- GC524135-Aminosalicylic Acid-d7Purity: >99.00%
An internal standard for the quantification of 5-aminosalicylic acid
- GC61187Pioglitazone D4CAS: 1134163-29-3Purity: >98%
An internal standard for the quantification of pioglitazone
- GC61436Gallic acid hydrateCAS: 5995-86-8Purity: >98.00%
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2).
- GC61895Ammonium iron(III) citrateCAS: 1185-57-5Purity: >98.00%
Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production.
- GC620333α-Hydroxy pravastatin sodiumCAS: 81093-43-8Purity: >98%
3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin.
- GC62643L-Buthionine-(S,R)-sulfoximine hydrochloridePurity: >99.00%
L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels.
- GC65095L-Glutamic acid-d5CAS: 2784-50-1Purity: >99.00%
L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid.
- GC65163Ardisiacrispin BCAS: 112766-96-8Purity: >98.00%
Ardisiacrispin B is a natural triterpenoid saponin compound isolated from the traditional Chinese medicinal plant Ardisia.
- GC70824Pioglitazone-d4 (alkyl)CAS: 1134163-31-7Purity: >98.00%
Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone.
- GC71730L-Glutathione reduced-13C2,15NCAS: 815610-65-2Purity: >99.50%
L-Glutathione reduced-13C2,15N is the 13C- and 15N-labeled L-Glutathione reduced.
- GC71837L-Glutamine-13C5,15N2,d5CAS: 2123439-02-9Purity: >99.00%
L-Glutamine-13C5,15N2,d5 is the deuterium, 13C-, and 15-labeled L-Glutamine.
- GC73223PROTAC GPX4 degrader-1CAS: 2916433-81-1Purity: >99.00%
PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
Cu-ATSP, a potent inhibitor of ferroptotic cell death, is almost 20-fold more potent than CuATSM. | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin is an effective and metabolically stable system xc- inhibitor and ferroptosis inducer. | ||||
| GC52290 | (R)-HTS-3 | 2771208-83-2 | >98.00% | |
An inhibitor of LPCAT3 | ||||
| GC52317 | BCP-T.A. | 2786829-70-5 | >98.00% | |
A ferroptosis inducer | ||||
| GC52413 | 5-Aminosalicylic Acid-d7 | - | >99.00% | |
An internal standard for the quantification of 5-aminosalicylic acid | ||||
| GC61187 | Pioglitazone D4 | 1134163-29-3 | >98% | |
An internal standard for the quantification of pioglitazone | ||||
| GC61436 | Gallic acid hydrate | 5995-86-8 | >98.00% | |
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). | ||||
| GC61895 | Ammonium iron(III) citrate | 1185-57-5 | >98.00% | |
Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production. | ||||
| GC62033 | 3α-Hydroxy pravastatin sodium | 81093-43-8 | >98% | |
3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. | ||||
| GC62643 | L-Buthionine-(S,R)-sulfoximine hydrochloride | - | >99.00% | |
L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. | ||||
| GC64352 | L-Glutamic acid-15N | 21160-87-2 | >98% | |
| GC65068 | L-Glutamine 15N | 80143-57-3 | >98.00% | |
| GC65095 | L-Glutamic acid-d5 | 2784-50-1 | >99.00% | |
L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid. | ||||
| GC65163 | Ardisiacrispin B | 112766-96-8 | >98.00% | |
Ardisiacrispin B is a natural triterpenoid saponin compound isolated from the traditional Chinese medicinal plant Ardisia. | ||||
| GC68479 | MMRi62 | 352693-80-2 | >99.00% | |
| GC68580 | 84-B10 | 698346-43-9 | >99.50% | |
84-B10 is a derivative of 3-phenylpentanedioic acid. It inhibits cisplatin-induced renal tubular iron death. 84-B10 alleviates mitochondrial damage and oxidative stress induced by cisplatin. 84-B10 improves acute kidney injury (AKI) induced by cisplatin. | ||||
| GC70157 | YL-939 | 3023925-68-7 | >98.50% | |
YL-939 is an effective inhibitor of ferroptosis. YL-939 inhibits ferroptosis by targeting PHB2/ferritin/iron axis. | ||||
| GC70824 | Pioglitazone-d4 (alkyl) | 1134163-31-7 | >98.00% | |
Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. | ||||
| GC71730 | L-Glutathione reduced-13C2,15N | 815610-65-2 | >99.50% | |
L-Glutathione reduced-13C2,15N is the 13C- and 15N-labeled L-Glutathione reduced. | ||||
| GC71837 | L-Glutamine-13C5,15N2,d5 | 2123439-02-9 | >99.00% | |
L-Glutamine-13C5,15N2,d5 is the deuterium, 13C-, and 15-labeled L-Glutamine. | ||||
| GC71839 | L-Cystine-d4 | 1192736-38-1 | >98.00% | |
L-Cystine-d4 is the deuterium labeled L-Cystine. | ||||
| GC71840 | L-Cystine-34S2 | 113512-08-6 | >98.00% | |
L-Cystine-34S2 is the 34S-labeled L-Cystine. | ||||
| GC72857 | HBED | 35998-29-9 | >98.00% | |
HBED is a potent iron chelator. | ||||
| GC73223 | PROTAC GPX4 degrader-1 | 2916433-81-1 | >99.00% | |
PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells. | ||||