Obesity

An ester form of 10-oxo-12(Z)-octadecenoic acid

An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid

A peptide orexin receptor 1 agonist

A sphingolipid

A sphingolipid

A satiety hormone

A growth hormone releasing peptide

A hypothalamic neuropeptide

Mazdutide is a long-acting dual agonist of the glucagon-like peptide-1 receptor (GLP-1R; K i =28.6nM) and the glucagon receptor (GCGR; K i =17.7nM).

Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor agonist.

Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively.

A metabolite of cortisol

Ipamorelin is a pentapeptide growth hormone secretagogue (GHS) and GHS receptor 1a (GHS-R1a) agonist.

Ppc-1 is a prenylated quinolinecarboxylic acid originally isolated from P. pseudo-candidum that has diverse biological activities.

Glucagon-like peptide 1 (GLP-1) (28-36) amide is a peptide and an active metabolite of the endogenous GLP-1R agonist GLP-1 (7-36) amide.

Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 is a cyclic peptide and an agonist of melanocortin receptor 4 (MC4R).

Taspoglutide is an agonist of the glucagon-like peptide 1 receptor (GLP-1R; Ki = 1.1 nM for the human receptor).

Glucagon-like peptide 1 (GLP-1) (7-36) acid is a derivative of the hormone and GLP-1 receptor (GLP-1R) agonist GLP-1 (7-36) amide.

KBP-066 is a dual amylin and calcitonin (CT) receptor agonist.

Liraglutide is a potent agonist of the glucagon-like peptide 1 (GLP-1) receptor and a synthetic derivative of GLP-1 (7-37) that contains a palmitic acid group.

NN1177 is a dual peptide agonist of the glucagon receptor (GCGR) and glucagon-like peptide 1 receptor (GLP-1R).

SAR441255 is a peptide triple agonist of the glucagon-like peptide 1 receptor (GLP-1R), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon receptor (GCGR).