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Vitamin D3-d7

Catalog No.GC40233

Vitamin D3-d7 is intended for use as an internal standard for the quantification of vitamin D3 by GC- or LC-MS.

Products are for research use only. Not for human use. We do not sell to patients.

Vitamin D3-d7 Chemical Structure

Cas No.: 1627523-19-6

Size Price Stock Qty
500μg
$1,113.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Vitamin D3-d7 is intended for use as an internal standard for the quantification of vitamin D3 by GC- or LC-MS. Vitamin D3 is a biologically inactive precursor to calcitriol that is converted to active metabolites in vivo. Vitamin D3 is obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3. Vitamin D3 can then be converted to 25-hydroxy vitamin D3 in the liver by the cytochrome P450 (CYP) isoform CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney. Formulations containing vitamin D3 have been used in the treatment of osteoporosis.

Chemical Properties

Cas No. 1627523-19-6 SDF
Canonical SMILES C=C1CC[C@H](O)C/C1=C/C=C2[C@@](CC[C@@]3([C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])[H])([H])[C@]3(C)CCC/2
Formula C27H37D7O M.Wt 391.7
Solubility Chloroform: Slightly Soluble,Methanol: Slightly Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.553 mL 12.7649 mL 25.5297 mL
5 mM 0.5106 mL 2.553 mL 5.1059 mL
10 mM 0.2553 mL 1.2765 mL 2.553 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

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Average Rating: 5 ★★★★★ (Based on Reviews and 17 reference(s) in Google Scholar.)

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