MAPK Signaling

TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.

BTX-6654 formate is a SOS1 PROTAC degrader.

SHP1‑IN‑2 is a selective and orally active SHP1 inhibitor.

7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound.

FZ1 peptide is a cyclic heptapeptide and also an integrin αvβ3 agonist.

Maxadilan TFA is a specific irreversible PAC1 receptor agonist and a potent vasodilator peptide present in the salivary glands of sand flies.

Glutathione trisulfide TFA (GSSSG TFA) is an orally active, blood-brain barrier permeable neuroprotective agent.

UE01 is an orally active, selective small-molecule modulator targeting both ULK1/ERK1/2.

Antabactin is an ABA receptor antagonist.

Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals.

CK37 is a competitive choline kinase-α inhibitor.

Hericene A is an orally active aromatic hericene derivative.

APS-2-79 (Standard) is the analytical standard of APS-2-79.

3-Ethoxy-5,6-dibromosalicylaldehyde is an IRE1/ERN1 inhibitor, with an IC 50 of 0.12 μM, a K i of 71-88 nM, and a K d of 100 nM against the ribonuclease activity of hIRE1α, as well as an IC 50 of 4.8 μM against yeast Ire1.

RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM.

Buforin IIb TFA (BF2-B TFA) is an anticancer peptide, as well as an Antibacterial and Antifungal agent.

Ein Hemmstoff von Ecto-5'-Nukleotidase.

Ein fluoreszierendes Derivat von GTP

Nedometinib is a MEK1 inhibitor (IC50 = 135 nM).

Lipoteichoic acid is a teichoic acid predominantly located in the cell walls of Gram-positive bacteria, widely involved in stimulating immune responses and cellular signaling pathways.

Keyhole limpet hemocyanin is a highly immunogenic copper-containing respiratory protein derived from the marine mollusk Megathura crenulata .

Hecubine is a natural aspidosperma-type alkaloid found in E. officinalis , with anti-neuroinflammation properties.

Isorhamnetin is a flavonoid compound extracted from the traditional Chinese medicine Hippophae rhamnoides L., possessing various biological activities including antioxidant, anti-inflammatory, anticancer, and neuroprotective effects.